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CASP10 caspase 10 [ Canis lupus familiaris (dog) ]

Gene ID: 488472, updated on 5-Mar-2024

Summary

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Official Symbol
CASP10provided by VGNC
Official Full Name
caspase 10provided by VGNC
Primary source
VGNC:VGNC:54928
See related
Ensembl:ENSCAFG00845029977
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human all
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Genomic context

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Location:
chromosome: 37
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (10220396..10255104)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (11199902..11234408)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (10173823..10208321)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (10201728..10236190)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (10180515..10215139)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867935 Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene CASP8 and FADD like apoptosis regulator Neighboring gene c-Myc-binding protein pseudogene Neighboring gene uncharacterized LOC111094451 Neighboring gene caspase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caspase-10
XP_005640587.1
XP_038303516.1
XP_038377577.1
XP_038441276.1
XP_038505681.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    10220396..10255104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447588.1 → XP_038303516.1  caspase-10

    UniProtKB/TrEMBL
    A0A8C0QUR4, A0A8C0TGH3, A0A8I3SCI1
    Related
    ENSCAFP00845041704.1, ENSCAFT00845053110.1
    Conserved Domains (3) summary
    smart00115
    Location:234 → 472
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08814
    Location:112 → 190
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:19 → 99
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    10201728..10236190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521649.1 → XP_038377577.1  caspase-10

    Conserved Domains (3) summary
    smart00115
    Location:234 → 472
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08814
    Location:112 → 190
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:19 → 99
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    10180515..10215139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649753.1 → XP_038505681.1  caspase-10

    Conserved Domains (3) summary
    smart00115
    Location:234 → 472
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08814
    Location:112 → 190
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:19 → 99
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    10173823..10208321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585348.1 → XP_038441276.1  caspase-10

    UniProtKB/TrEMBL
    A0A8C0QUR4, A0A8C0TGH3, A0A8I3SCI1
    Conserved Domains (3) summary
    smart00115
    Location:234 → 472
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08814
    Location:112 → 190
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:19 → 99
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11199902..11234408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005640530.4 → XP_005640587.1  caspase-10

    UniProtKB/TrEMBL
    A0A8C0QUR4, A0A8C0TGH3, A0A8I3SCI1
    Conserved Domains (3) summary
    smart00115
    Location:234 → 472
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08814
    Location:112 → 190
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:19 → 99
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein
Heading Accession and Version

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