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CFLAR CASP8 and FADD like apoptosis regulator [ Canis lupus familiaris (dog) ]

Gene ID: 488471, updated on 5-Mar-2024

Summary

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Official Symbol
CFLARprovided by VGNC
Official Full Name
CASP8 and FADD like apoptosis regulatorprovided by VGNC
Primary source
VGNC:VGNC:39178
See related
Ensembl:ENSCAFG00845029893
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 37
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (10173456..10212316)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (11153354..11191827)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (10126854..10165741)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (10154909..10193670)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (10133242..10172157)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867935 Neighboring gene U6 spliceosomal RNA Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene caspase 10 Neighboring gene c-Myc-binding protein pseudogene Neighboring gene uncharacterized LOC111094451

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CASP8 and FADD-like apoptosis regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    10173456..10212316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447575.1 → XP_038303503.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  2. XM_038447585.1 → XP_038303513.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  3. XM_038447578.1 → XP_038303506.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Related
    ENSCAFP00845041639.1, ENSCAFT00845053032.1
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  4. XM_038447574.1 → XP_038303502.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  5. XM_038447576.1 → XP_038303504.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  6. XM_038447577.1 → XP_038303505.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  7. XM_038447573.1 → XP_038303501.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Related
    ENSCAFP00845041606.1, ENSCAFT00845052991.1
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  8. XM_038447586.1 → XP_038303514.1  CASP8 and FADD-like apoptosis regulator isoform X2

    UniProtKB/TrEMBL
    A0A8C0JQH8, A0A8I3SCH8, A0A8P0NPK7
    Related
    ENSCAFP00845041668.1, ENSCAFT00845053068.1
    Conserved Domains (2) summary
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  9. XM_038447581.1 → XP_038303509.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  10. XM_038447583.1 → XP_038303511.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  11. XM_038447580.1 → XP_038303508.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  12. XM_038447582.1 → XP_038303510.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  13. XM_038447579.1 → XP_038303507.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  14. XM_038447587.1 → XP_038303515.1  CASP8 and FADD-like apoptosis regulator isoform X3

    Conserved Domains (1) summary
    cl00042
    Location:1 → 233
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    10154909..10193670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521636.1 → XP_038377564.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  2. XM_038521646.1 → XP_038377574.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  3. XM_038521639.1 → XP_038377567.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  4. XM_038521637.1 → XP_038377565.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  5. XM_038521638.1 → XP_038377566.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  6. XM_038521635.1 → XP_038377563.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  7. XM_038521634.1 → XP_038377562.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  8. XM_038521647.1 → XP_038377575.1  CASP8 and FADD-like apoptosis regulator isoform X2

    Conserved Domains (2) summary
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  9. XM_038521642.1 → XP_038377570.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  10. XM_038521644.1 → XP_038377572.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  11. XM_038521641.1 → XP_038377569.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  12. XM_038521643.1 → XP_038377571.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  13. XM_038521640.1 → XP_038377568.1  CASP8 and FADD-like apoptosis regulator isoform X1

    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  14. XM_038521648.1 → XP_038377576.1  CASP8 and FADD-like apoptosis regulator isoform X3

    Conserved Domains (1) summary
    cl00042
    Location:1 → 233
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    10133242..10172157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649741.1 → XP_038505669.1  CASP8 and FADD-like apoptosis regulator isoform X1

  2. XM_038649750.1 → XP_038505678.1  CASP8 and FADD-like apoptosis regulator isoform X1

  3. XM_038649744.1 → XP_038505672.1  CASP8 and FADD-like apoptosis regulator isoform X1

  4. XM_038649740.1 → XP_038505668.1  CASP8 and FADD-like apoptosis regulator isoform X1

  5. XM_038649742.1 → XP_038505670.1  CASP8 and FADD-like apoptosis regulator isoform X1

  6. XM_038649743.1 → XP_038505671.1  CASP8 and FADD-like apoptosis regulator isoform X1

  7. XM_038649739.1 → XP_038505667.1  CASP8 and FADD-like apoptosis regulator isoform X1

  8. XM_038649751.1 → XP_038505679.1  CASP8 and FADD-like apoptosis regulator isoform X2

    Conserved Domains (2) summary
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  9. XM_038649747.1 → XP_038505675.1  CASP8 and FADD-like apoptosis regulator isoform X1

  10. XM_038649749.1 → XP_038505677.1  CASP8 and FADD-like apoptosis regulator isoform X1

  11. XM_038649746.1 → XP_038505674.1  CASP8 and FADD-like apoptosis regulator isoform X1

  12. XM_038649748.1 → XP_038505676.1  CASP8 and FADD-like apoptosis regulator isoform X1

  13. XM_038649745.1 → XP_038505673.1  CASP8 and FADD-like apoptosis regulator isoform X1

  14. XM_038649752.1 → XP_038505680.1  CASP8 and FADD-like apoptosis regulator isoform X3

    Conserved Domains (1) summary
    cl00042
    Location:1 → 233
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    10126854..10165741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585336.1 → XP_038441264.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  2. XM_038585345.1 → XP_038441273.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  3. XM_038585339.1 → XP_038441267.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  4. XM_038585335.1 → XP_038441263.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  5. XM_038585337.1 → XP_038441265.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  6. XM_038585338.1 → XP_038441266.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  7. XM_038585334.1 → XP_038441262.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  8. XM_038585346.1 → XP_038441274.1  CASP8 and FADD-like apoptosis regulator isoform X2

    UniProtKB/TrEMBL
    A0A8C0JQH8, A0A8I3SCH8, A0A8P0NPK7
    Conserved Domains (2) summary
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  9. XM_038585342.1 → XP_038441270.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  10. XM_038585344.1 → XP_038441272.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  11. XM_038585341.1 → XP_038441269.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  12. XM_038585343.1 → XP_038441271.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  13. XM_038585340.1 → XP_038441268.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  14. XM_038585347.1 → XP_038441275.1  CASP8 and FADD-like apoptosis regulator isoform X3

    Conserved Domains (1) summary
    cl00042
    Location:1 → 233
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11153354..11191827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038463609.1 → XP_038319537.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  2. XM_038463618.1 → XP_038319546.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  3. XM_038463613.1 → XP_038319541.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  4. XM_545592.7 → XP_545592.3  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  5. XM_038463610.1 → XP_038319538.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  6. XM_038463611.1 → XP_038319539.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  7. XM_005640531.4 → XP_005640588.2  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  8. XM_022414975.2 → XP_022270683.1  CASP8 and FADD-like apoptosis regulator isoform X2

    UniProtKB/TrEMBL
    A0A8C0JQH8, A0A8I3SCH8, A0A8P0NPK7
    Conserved Domains (2) summary
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  9. XM_038463615.1 → XP_038319543.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  10. XM_038463617.1 → XP_038319545.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  11. XM_005640535.4 → XP_005640592.2  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  12. XM_038463616.1 → XP_038319544.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  13. XM_038463614.1 → XP_038319542.1  CASP8 and FADD-like apoptosis regulator isoform X1

    UniProtKB/TrEMBL
    A0A8C0JSV4, A0A8C0TCR1, A0A8I3Q4N3, A0A8I3QL91, A0A8P0SHA3
    Conserved Domains (3) summary
    smart00115
    Location:273 → 507
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
    cd08337
    Location:28 → 107
    DED_c-FLIP_r1; Death Effector Domain, repeat 1, of cellular FLICE-Inhibitory Protein
    cd08340
    Location:118 → 198
    DED_c-FLIP_r2; Death Effector Domain, repeat 2, of cellular FLICE-Inhibitory Protein

  14. XM_014111006.3 → XP_013966481.1  CASP8 and FADD-like apoptosis regulator isoform X3

    Conserved Domains (1) summary
    cl00042
    Location:1 → 233
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
Nucleotide Protein
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