U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ITGB6 integrin subunit beta 6 [ Canis lupus familiaris (dog) ]

Gene ID: 488368, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ITGB6provided by VGNC
Official Full Name
integrin subunit beta 6provided by VGNC
Primary source
VGNC:VGNC:42141
See related
Ensembl:ENSCAFG00845029158
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ITGB6 in Genome Data Viewer
Location:
chromosome: 36
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (5957679..6086682, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (5972263..6101021, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (6127531..6256234, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (5974904..6103502, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (6018081..6146821, complement)

Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S23-like Neighboring gene phospholipase A2 receptor 1 Neighboring gene uncharacterized LOC111094230 Neighboring gene uncharacterized LOC111094185 Neighboring gene RNA binding motif single stranded interacting protein 1 Neighboring gene actin, cytoplasmic 1-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin alphav-beta6 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
integrin beta-6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051840.1 Reference ROS_Cfam_1.0

    Range
    5957679..6086682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038446866.1 → XP_038302794.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NCE4
    Conserved Domains (5) summary
    smart00187
    Location:50 → 473
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:643 → 725
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:750 → 793
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:475 → 504
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:486 → 659
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038446869.1 → XP_038302797.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Related
    ENSCAFP00845040798.1, ENSCAFT00845052002.1
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038446865.1 → XP_038302793.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8I3S743
    Conserved Domains (5) summary
    smart00187
    Location:50 → 474
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:751 → 794
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:476 → 505
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:487 → 660
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038446867.1 → XP_038302795.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Related
    ENSCAFP00845040699.1, ENSCAFT00845051876.1
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  5. XM_038446868.1 → XP_038302796.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  6. XM_038446864.1 → XP_038302792.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8I3S743
    Related
    ENSCAFP00845040749.1, ENSCAFT00845051939.1
    Conserved Domains (5) summary
    smart00187
    Location:50 → 474
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:751 → 794
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:476 → 505
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:487 → 660
    exchanger_TraA; outer membrane exchange protein TraA

  7. XM_038446870.1 → XP_038302798.1  integrin beta-6 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SCB1
    Related
    ENSCAFP00845040857.1, ENSCAFT00845052089.1
    Conserved Domains (5) summary
    pfam07965
    Location:551 → 633
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:658 → 701
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:383 → 412
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:394 → 567
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:36 → 381
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049296.1 Alternate UMICH_Zoey_3.1

    Range
    5974904..6103502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038520938.1 → XP_038376866.1  integrin beta-6 isoform X2

    Conserved Domains (5) summary
    smart00187
    Location:50 → 473
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:643 → 725
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:750 → 793
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:475 → 504
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:486 → 659
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038520942.1 → XP_038376870.1  integrin beta-6 isoform X3

  3. XM_038520937.1 → XP_038376865.1  integrin beta-6 isoform X1

  4. XM_038520939.1 → XP_038376867.1  integrin beta-6 isoform X3

  5. XM_038520940.1 → XP_038376868.1  integrin beta-6 isoform X3

  6. XM_038520936.1 → XP_038376864.1  integrin beta-6 isoform X1

  7. XM_038520943.1 → XP_038376871.1  integrin beta-6 isoform X4

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

    Range
    6018081..6146821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649054.1 → XP_038504982.1  integrin beta-6 isoform X2

  2. XM_038649057.1 → XP_038504985.1  integrin beta-6 isoform X3

  3. XM_038649053.1 → XP_038504981.1  integrin beta-6 isoform X1

  4. XM_038649055.1 → XP_038504983.1  integrin beta-6 isoform X3

  5. XM_038649056.1 → XP_038504984.1  integrin beta-6 isoform X3

  6. XM_038649052.1 → XP_038504980.1  integrin beta-6 isoform X1

  7. XM_038649058.1 → XP_038504986.1  integrin beta-6 isoform X4

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

    Range
    6127531..6256234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038584632.1 → XP_038440560.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NCE4
    Conserved Domains (5) summary
    smart00187
    Location:50 → 473
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:643 → 725
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:750 → 793
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:475 → 504
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:486 → 659
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038584635.1 → XP_038440563.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038584631.1 → XP_038440559.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8I3S743
    Conserved Domains (5) summary
    smart00187
    Location:50 → 474
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:751 → 794
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:476 → 505
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:487 → 660
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038584633.1 → XP_038440561.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  5. XM_038584634.1 → XP_038440562.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Z3Z7
    Conserved Domains (5) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:731 → 774
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:456 → 485
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:467 → 640
    exchanger_TraA; outer membrane exchange protein TraA

  6. XM_038584630.1 → XP_038440558.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8I3S743
    Conserved Domains (5) summary
    smart00187
    Location:50 → 474
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:751 → 794
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:476 → 505
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:487 → 660
    exchanger_TraA; outer membrane exchange protein TraA

  7. XM_038584636.1 → XP_038440564.1  integrin beta-6 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SCB1
    Conserved Domains (5) summary
    pfam07965
    Location:551 → 633
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:658 → 701
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:383 → 412
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:394 → 567
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:36 → 381
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5972263..6101021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038463341.1 → XP_038319269.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NCE4
    Conserved Domains (5) summary
    smart00187
    Location:50 → 473
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:643 → 725
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:750 → 793
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:475 → 504
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:486 → 659
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_005640232.4 → XP_005640289.1  integrin beta-6 isoform X3

    See identical proteins and their annotated locations for XP_005640289.1

    UniProtKB/TrEMBL
    A0A8C0N458, A0A8C0Z3Z7
    Conserved Domains (3) summary
    pfam00362
    Location:30 → 454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  3. XM_014110782.3 → XP_013966257.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8C0TDZ7, A0A8P0NVZ4
    Conserved Domains (3) summary
    pfam00362
    Location:50 → 474
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:753 → 795
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  4. XM_005640230.4 → XP_005640287.1  integrin beta-6 isoform X3

    See identical proteins and their annotated locations for XP_005640287.1

    UniProtKB/TrEMBL
    A0A8C0N458, A0A8C0Z3Z7
    Conserved Domains (3) summary
    pfam00362
    Location:30 → 454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  5. XM_005640231.4 → XP_005640288.1  integrin beta-6 isoform X3

    See identical proteins and their annotated locations for XP_005640288.1

    UniProtKB/TrEMBL
    A0A8C0N458, A0A8C0Z3Z7
    Conserved Domains (3) summary
    pfam00362
    Location:30 → 454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  6. XM_014110780.3 → XP_013966255.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NCE4, A0A8C0TDZ7, A0A8P0NVZ4
    Conserved Domains (3) summary
    pfam00362
    Location:50 → 474
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:644 → 726
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:753 → 795
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  7. XM_014110783.3 → XP_013966258.1  integrin beta-6 isoform X4

    UniProtKB/TrEMBL
    A0A8C0TE38, A0A8P0NVB3
    Conserved Domains (3) summary
    pfam00362
    Location:36 → 381
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:551 → 633
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:660 → 702
    Integrin_b_cyt; Integrin beta cytoplasmic domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous