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TNK2 tyrosine kinase non receptor 2 [ Canis lupus familiaris (dog) ]

Gene ID: 488025, updated on 5-Mar-2024

Summary

Official Symbol
TNK2provided by VGNC
Official Full Name
tyrosine kinase non receptor 2provided by VGNC
Primary source
VGNC:VGNC:47680
See related
Ensembl:ENSCAFG00845029652
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 33
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (29386486..29428984, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (29178360..29220811, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (29848891..29891309, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (29171866..29196006, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (29227984..29270384, complement)

Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093734 Neighboring gene mucin-5AC-like Neighboring gene mucin 4, cell surface associated Neighboring gene transferrin receptor Neighboring gene S-adenosylmethionine decarboxylase proenzyme-like

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
activated CDC42 kinase 1; LOW QUALITY PROTEIN: activated CDC42 kinase 1
XP_038301168.1
XP_038301169.1
XP_038301170.1
XP_038301171.1
XP_038301172.1
XP_038301173.1
XP_038301174.1
XP_038301175.1
XP_038301176.1
XP_038301177.1
XP_038301178.1
XP_038301179.1
XP_038301180.1
XP_038301181.1
XP_038301182.1
XP_038301183.1
XP_038301184.1
XP_038318250.1
XP_038318251.1
XP_038318252.1
XP_038318253.1
XP_038318254.1
XP_038318255.1
XP_038318256.1
XP_038318257.1
XP_038318259.1
XP_038318260.1
XP_038318261.1
XP_038318262.1
XP_038318263.1
XP_038318264.1
XP_038318265.1
XP_038375523.1
XP_038439042.1
XP_038439043.1
XP_038439044.1
XP_038439045.1
XP_038439046.1
XP_038439047.1
XP_038439048.1
XP_038439049.1
XP_038439050.1
XP_038439051.1
XP_038439052.1
XP_038439053.1
XP_038439054.1
XP_038439055.1
XP_038439056.1
XP_038439057.1
XP_038439058.1
XP_038503458.1
XP_038503459.1
XP_038503460.1
XP_038503461.1
XP_038503462.1
XP_038503463.1
XP_038503464.1
XP_038503465.1
XP_038503466.1
XP_038503467.1
XP_038503468.1
XP_038503469.1
XP_038503470.1
XP_038503471.1
XP_038503472.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051837.1 Reference ROS_Cfam_1.0

    Range
    29386486..29428984 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445245.1XP_038301173.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6191001
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10031046
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10331072
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:816880
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  2. XM_038445247.1XP_038301175.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6191001
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10031046
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10331072
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:816880
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  3. XM_038445242.1XP_038301170.1  activated CDC42 kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0JQK5
    Conserved Domains (8) summary
    cd09539
    Location:3394
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6461028
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10301073
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10601099
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:157414
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:476541
    GTPase_binding; GTPase binding
    pfam11555
    Location:843907
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:422471
    SH3_9; Variant SH3 domain
  4. XM_038445255.1XP_038301183.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:551934
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:935978
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:9651004
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:748812
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  5. XM_038445246.1XP_038301174.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6191001
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10031046
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10331072
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:816880
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  6. XM_038445248.1XP_038301176.1  activated CDC42 kinase 1 isoform X7

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Related
    ENSCAFP00845041417.1, ENSCAFT00845052758.1
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8311033
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:10331072
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:848912
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  7. XM_038445240.1XP_038301168.1  activated CDC42 kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6511033
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10351078
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10651104
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:848912
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  8. XM_038445249.1XP_038301177.1  activated CDC42 kinase 1 isoform X8

    UniProtKB/TrEMBL
    A0A8I3Q4D0, A0A8I3Q4I5
    Related
    ENSCAFP00845041298.1, ENSCAFT00845052621.1
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  9. XM_038445243.1XP_038301171.1  activated CDC42 kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Related
    ENSCAFP00845041394.1, ENSCAFT00845052733.1
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  10. XM_038445254.1XP_038301182.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:551934
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:935978
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:9651004
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:748812
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  11. XM_038445256.1XP_038301184.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:551934
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:935978
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:9651004
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:748812
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  12. XM_038445252.1XP_038301180.1  activated CDC42 kinase 1 isoform X11

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:9931032
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  13. XM_038445250.1XP_038301178.1  activated CDC42 kinase 1 isoform X9

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  14. XM_038445251.1XP_038301179.1  activated CDC42 kinase 1 isoform X10

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8061008
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  15. XM_038445241.1XP_038301169.1  activated CDC42 kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6511033
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10351078
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10651104
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:848912
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  16. XM_038445244.1XP_038301172.1  activated CDC42 kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  17. XM_038445253.1XP_038301181.1  activated CDC42 kinase 1 isoform X12

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (6) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8311033
    PHA03247; large tegument protein UL36; Provisional
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:848912
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049293.1 Alternate UMICH_Zoey_3.1

    Range
    29171866..29196006 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038519595.1XP_038375523.1  LOW QUALITY PROTEIN: activated CDC42 kinase 1 isoform X14

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

    Range
    29227984..29270384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038647535.1XP_038503463.1  activated CDC42 kinase 1 isoform X20

  2. XM_038647537.1XP_038503465.1  activated CDC42 kinase 1 isoform X20

  3. XM_038647532.1XP_038503460.1  activated CDC42 kinase 1 isoform X17

  4. XM_038647544.1XP_038503472.1  activated CDC42 kinase 1 isoform X25

  5. XM_038647536.1XP_038503464.1  activated CDC42 kinase 1 isoform X20

  6. XM_038647538.1XP_038503466.1  activated CDC42 kinase 1 isoform X21

  7. XM_038647533.1XP_038503461.1  activated CDC42 kinase 1 isoform X18

  8. XM_038647530.1XP_038503458.1  activated CDC42 kinase 1 isoform X15

  9. XM_038647542.1XP_038503470.1  activated CDC42 kinase 1 isoform X25

  10. XM_038647543.1XP_038503471.1  activated CDC42 kinase 1 isoform X25

  11. XM_038647540.1XP_038503468.1  activated CDC42 kinase 1 isoform X23

  12. XM_038647539.1XP_038503467.1  activated CDC42 kinase 1 isoform X22

  13. XM_038647534.1XP_038503462.1  activated CDC42 kinase 1 isoform X19

  14. XM_038647531.1XP_038503459.1  activated CDC42 kinase 1 isoform X16

  15. XM_038647541.1XP_038503469.1  activated CDC42 kinase 1 isoform X24

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

    Range
    29848891..29891309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583119.1XP_038439047.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
  2. XM_038583121.1XP_038439049.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
  3. XM_038583116.1XP_038439044.1  activated CDC42 kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0JQK5
  4. XM_038583129.1XP_038439057.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
  5. XM_038583120.1XP_038439048.1  activated CDC42 kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q4I5
  6. XM_038583122.1XP_038439050.1  activated CDC42 kinase 1 isoform X7

    UniProtKB/TrEMBL
    A0A8I3Q8I9
  7. XM_038583114.1XP_038439042.1  activated CDC42 kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q4I5
  8. XM_038583123.1XP_038439051.1  activated CDC42 kinase 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0JQK5, A0A8C0P937, A0A8P0P0L5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  9. XM_038583117.1XP_038439045.1  activated CDC42 kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PCY4, A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  10. XM_038583128.1XP_038439056.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
  11. XM_038583130.1XP_038439058.1  activated CDC42 kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A8C0P8P4
  12. XM_038583126.1XP_038439054.1  activated CDC42 kinase 1 isoform X11

    UniProtKB/TrEMBL
    A0A8C0JPR4
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:9931032
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  13. XM_038583125.1XP_038439053.1  activated CDC42 kinase 1 isoform X10

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8061008
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  14. XM_038583115.1XP_038439043.1  activated CDC42 kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q4I5
  15. XM_038583124.1XP_038439052.1  activated CDC42 kinase 1 isoform X9

    UniProtKB/TrEMBL
    A0A8C0JQK5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  16. XM_038583118.1XP_038439046.1  activated CDC42 kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  17. XM_038583127.1XP_038439055.1  activated CDC42 kinase 1 isoform X12

    UniProtKB/TrEMBL
    A0A8I3Q8I9

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29178360..29220811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038462327.1XP_038318255.1  activated CDC42 kinase 1 isoform X27

    UniProtKB/TrEMBL
    A0A8I3Q4I5, A0A8P0NXH2
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:594976
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9781021
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:791855
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  2. XM_038462329.1XP_038318257.1  activated CDC42 kinase 1 isoform X27

    UniProtKB/TrEMBL
    A0A8I3Q4I5, A0A8P0NXH2
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:594976
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9781021
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:791855
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  3. XM_038462324.1XP_038318252.1  activated CDC42 kinase 1 isoform X26

    UniProtKB/TrEMBL
    A0A8C0JQK5, A0A8C0NZG8
    Conserved Domains (8) summary
    cd09539
    Location:3394
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6211003
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10051048
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10351074
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:157414
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:476541
    GTPase_binding; GTPase binding
    pfam11555
    Location:818882
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:422471
    SH3_9; Variant SH3 domain
  4. XM_038462336.1XP_038318264.1  activated CDC42 kinase 1 isoform X30

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:526909
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:910953
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:940979
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:723787
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  5. XM_038462328.1XP_038318256.1  activated CDC42 kinase 1 isoform X27

    UniProtKB/TrEMBL
    A0A8I3Q4I5, A0A8P0NXH2
    Conserved Domains (8) summary
    cd09539
    Location:667
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:594976
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9781021
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:130387
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:449514
    GTPase_binding; GTPase binding
    pfam11555
    Location:791855
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:395444
    SH3_9; Variant SH3 domain
  6. XM_038462331.1XP_038318259.1  activated CDC42 kinase 1 isoform X28

    UniProtKB/TrEMBL
    A0A8C0P038, A0A8I3Q8I9
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8061008
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  7. XM_038462325.1XP_038318253.1  activated CDC42 kinase 1 isoform X8

    UniProtKB/TrEMBL
    A0A8C0JQK5, A0A8C0P937, A0A8P0P0L5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  8. XM_038462322.1XP_038318250.1  activated CDC42 kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PCY4, A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  9. XM_038462335.1XP_038318263.1  activated CDC42 kinase 1 isoform X30

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:526909
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:910953
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:940979
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:723787
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  10. XM_038462337.1XP_038318265.1  activated CDC42 kinase 1 isoform X30

    UniProtKB/TrEMBL
    A0A8C0P8P4
    Conserved Domains (7) summary
    PHA03247
    Location:526909
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:910953
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:940979
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:62319
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:381446
    GTPase_binding; GTPase binding
    pfam11555
    Location:723787
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:327376
    SH3_9; Variant SH3 domain
  11. XM_038462333.1XP_038318261.1  activated CDC42 kinase 1 isoform X11

    UniProtKB/TrEMBL
    A0A8C0JPR4
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:9931032
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  12. XM_038462332.1XP_038318260.1  activated CDC42 kinase 1 isoform X10

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (7) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8061008
    PHA03247; large tegument protein UL36; Provisional
    cd14328
    Location:10081047
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  13. XM_038462326.1XP_038318254.1  activated CDC42 kinase 1 isoform X9

    UniProtKB/TrEMBL
    A0A8C0JQK5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:791993
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:9951038
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10251064
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:808872
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  14. XM_038462323.1XP_038318251.1  activated CDC42 kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q4I5
    Conserved Domains (8) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:6261008
    PHA03247; large tegument protein UL36; Provisional
    cd14274
    Location:10101053
    UBA_ACK1; UBA domain found in activated Cdc42 kinase 1 (ACK1) and similar proteins
    cd14328
    Location:10401079
    UBA_TNK1; UBA domain found in non-receptor tyrosine-protein kinase TNK1 and similar proteins
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain
  15. XM_038462334.1XP_038318262.1  activated CDC42 kinase 1 isoform X29

    UniProtKB/TrEMBL
    A0A8I3Q8I9
    Conserved Domains (6) summary
    cd09539
    Location:3899
    SAM_TNK-like; SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases
    PHA03247
    Location:8061008
    PHA03247; large tegument protein UL36; Provisional
    cd05040
    Location:162419
    PTKc_Ack_like; Catalytic domain of the Protein Tyrosine Kinase, Activated Cdc42-associated kinase
    pfam09027
    Location:481546
    GTPase_binding; GTPase binding
    pfam11555
    Location:823887
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6
    pfam14604
    Location:427476
    SH3_9; Variant SH3 domain