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HDC histidine decarboxylase [ Canis lupus familiaris (dog) ]

Gene ID: 487551, updated on 5-Mar-2024

Summary

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Official Symbol
HDCprovided by VGNC
Official Full Name
histidine decarboxylaseprovided by VGNC
Primary source
VGNC:VGNC:41625
See related
Ensembl:ENSCAFG00845023453
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 30
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (16345121..16367075, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (16127350..16149277, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (16491552..16513689, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (16267658..16289600, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (16385120..16407243, complement)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase DDX18-like Neighboring gene uncharacterized LOC119866888 Neighboring gene solute carrier family 27 member 2 Neighboring gene GA binding protein transcription factor subunit beta 1 Neighboring gene ubiquitin specific peptidase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histidine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in histamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in histidine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histidine decarboxylase
XP_038298235.1
XP_038372682.1
XP_038436322.1
XP_038500615.1
XP_544676.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    16345121..16367075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442307.1 → XP_038298235.1  histidine decarboxylase

    UniProtKB/TrEMBL
    A0A8C0T5X1, A0A8C0Z2J6, A0A8I3PEM1, A0A8I3PM83
    Related
    ENSCAFP00845032480.1, ENSCAFT00845041423.1
    Conserved Domains (1) summary
    pfam00282
    Location:36 → 414
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    16267658..16289600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516754.1 → XP_038372682.1  histidine decarboxylase

    Conserved Domains (1) summary
    pfam00282
    Location:36 → 414
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    16385120..16407243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644687.1 → XP_038500615.1  histidine decarboxylase

    Conserved Domains (1) summary
    pfam00282
    Location:36 → 414
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    16491552..16513689 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580394.1 → XP_038436322.1  histidine decarboxylase

    UniProtKB/TrEMBL
    A0A8C0PIZ2, A0A8C0Q008
    Conserved Domains (1) summary
    pfam00282
    Location:36 → 414
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16127350..16149277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544676.7 → XP_544676.3  histidine decarboxylase

    UniProtKB/TrEMBL
    A0A8C0T5X1, A0A8C0Z2J6, A0A8I3PEM1, A0A8I3PM83
    Conserved Domains (1) summary
    pfam00282
    Location:36 → 414
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain
Nucleotide Protein
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