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CHRM5 cholinergic receptor muscarinic 5 [ Canis lupus familiaris (dog) ]

Gene ID: 487472, updated on 5-Mar-2024

Summary

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Official Symbol
CHRM5provided by VGNC
Official Full Name
cholinergic receptor muscarinic 5provided by VGNC
Primary source
VGNC:VGNC:39235
See related
Ensembl:ENSCAFG00845020291
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 30
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (1086979..1172509, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (1033732..1118973, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (1260343..1345796, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (1033678..1119068, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (1132741..1218246, complement)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102151917 Neighboring gene uncharacterized LOC119866856 Neighboring gene uncharacterized LOC111093276 Neighboring gene ER membrane protein complex subunit 7 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene apoptosis and caspase activation inhibitor Neighboring gene uncharacterized LOC111093275 Neighboring gene ryanodine receptor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled acetylcholine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gastric acid secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
muscarinic acetylcholine receptor M5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    1086979..1172509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441829.1 → XP_038297757.1  muscarinic acetylcholine receptor M5

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Related
    ENSCAFP00845027955.1, ENSCAFT00845035731.1
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038441830.1 → XP_038297758.1  muscarinic acetylcholine receptor M5

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    1033678..1119068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516318.1 → XP_038372246.1  muscarinic acetylcholine receptor M5

    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038516319.1 → XP_038372247.1  muscarinic acetylcholine receptor M5

    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RNA

  1. XR_005347662.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    1132741..1218246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644168.1 → XP_038500096.1  muscarinic acetylcholine receptor M5

    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038644169.1 → XP_038500097.1  muscarinic acetylcholine receptor M5

    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    1260343..1345796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579913.1 → XP_038435841.1  muscarinic acetylcholine receptor M5

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038579914.1 → XP_038435842.1  muscarinic acetylcholine receptor M5

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RNA

  1. XR_005381403.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1033732..1118973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005638190.4 → XP_005638247.1  muscarinic acetylcholine receptor M5

    See identical proteins and their annotated locations for XP_005638247.1

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038461107.1 → XP_038317035.1  muscarinic acetylcholine receptor M5

    UniProtKB/TrEMBL
    A0A8C0K958, A0A8C0P4S2, A0A8I3PH67, A0A8P0NM30
    Conserved Domains (2) summary
    cd14964
    Location:32 → 58
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 225
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RNA

  1. XR_005316300.1 RNA Sequence

Nucleotide Protein
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