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ITGA8 integrin subunit alpha 8 [ Canis lupus familiaris (dog) ]

Gene ID: 487119, updated on 5-Mar-2024

Summary

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Official Symbol
ITGA8provided by VGNC
Official Full Name
integrin subunit alpha 8provided by VGNC
Primary source
VGNC:VGNC:42130
See related
Ensembl:ENSCAFG00845014426
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ITGA8 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
30
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (21368356..21544465)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (18185585..18354528)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (20034706..20203972)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (18574970..18744463)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (19409413..19578983)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091466 Neighboring gene MINDY lysine 48 deubiquitinase 3 Neighboring gene uncharacterized LOC119870137 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102154598

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    21368356..21544465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038658346.1 → XP_038514274.1  integrin alpha-8

    UniProtKB/TrEMBL
    A0A8C0K5R2, A0A8I3S0V6
    Related
    ENSCAFP00845020348.1, ENSCAFT00845025825.1
    Conserved Domains (3) summary
    smart00191
    Location:382 → 436
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:1034 → 1048
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:482 → 933
    Integrin_alpha2; Integrin alpha

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    18574970..18744463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038469281.1 → XP_038325209.1  integrin alpha-8

    Conserved Domains (3) summary
    smart00191
    Location:382 → 436
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:1034 → 1048
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:482 → 933
    Integrin_alpha2; Integrin alpha

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    19409413..19578983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038594277.1 → XP_038450205.1  integrin alpha-8

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    20034706..20203972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038530016.1 → XP_038385944.1  integrin alpha-8

    UniProtKB/TrEMBL
    A0A8C0K5R2, A0A8C0RWF6, A0A8P0SA99
    Conserved Domains (3) summary
    smart00191
    Location:382 → 436
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:1034 → 1048
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:482 → 933
    Integrin_alpha2; Integrin alpha

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18185585..18354528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456809.1 → XP_038312737.1  integrin alpha-8

    UniProtKB/TrEMBL
    A0A8C0K5R2, A0A8C0RWF6, A0A8P0SA99
    Conserved Domains (3) summary
    smart00191
    Location:382 → 436
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:1034 → 1048
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:482 → 933
    Integrin_alpha2; Integrin alpha
Nucleotide Protein
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