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CYP7B1 cytochrome P450 family 7 subfamily B member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 486973, updated on 5-Mar-2024

Summary

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Official Symbol
CYP7B1provided by VGNC
Official Full Name
cytochrome P450 family 7 subfamily B member 1provided by VGNC
Primary source
VGNC:VGNC:50379
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 29
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (14537942..14712338, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (14762658..14936799, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (14932049..15106453, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (14550483..14724576, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (14664658..14838558, complement)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866672 Neighboring gene basic helix-loop-helix family member e22 Neighboring gene uncharacterized LOC102153932 Neighboring gene uncharacterized LOC119866704 Neighboring gene uncharacterized LOC111093165 Neighboring gene programmed cell death protein 6-like Neighboring gene uncharacterized LOC102154275

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
25-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450 7B1
Names
cytochrome P450, family 7, subfamily B, polypeptide 1
XP_005638074.1
XP_005638076.1
XP_022268148.1
XP_038297184.1
XP_038297185.1
XP_038297186.1
XP_038297188.1
XP_038316791.1
XP_038371763.1
XP_038371764.1
XP_038371765.1
XP_038371766.1
XP_038435324.1
XP_038435325.1
XP_038435326.1
XP_038435327.1
XP_038499571.1
XP_038499572.1
XP_038499573.1
XP_038499574.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    14537942..14712338 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441256.1 → XP_038297184.1  cytochrome P450 7B1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RK05, A0A8P0N9M7
    Conserved Domains (1) summary
    cl41757
    Location:66 → 498
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038441257.1 → XP_038297185.1  cytochrome P450 7B1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NFX8, A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:45 → 477
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_038441260.1 → XP_038297188.1  cytochrome P450 7B1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:1 → 399
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  4. XM_038441258.1 → XP_038297186.1  cytochrome P450 7B1 isoform X3

    Conserved Domains (1) summary
    cl41757
    Location:66 → 407
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    14550483..14724576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515835.1 → XP_038371763.1  cytochrome P450 7B1 isoform X1

    Conserved Domains (1) summary
    cl41757
    Location:66 → 498
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038515836.1 → XP_038371764.1  cytochrome P450 7B1 isoform X2

    Conserved Domains (1) summary
    cl41757
    Location:45 → 477
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_038515838.1 → XP_038371766.1  cytochrome P450 7B1 isoform X4

    Conserved Domains (1) summary
    cl41757
    Location:1 → 399
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  4. XM_038515837.1 → XP_038371765.1  cytochrome P450 7B1 isoform X3

    Conserved Domains (1) summary
    cl41757
    Location:66 → 407
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    14664658..14838558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643643.1 → XP_038499571.1  cytochrome P450 7B1 isoform X1

    Conserved Domains (1) summary
    cl41757
    Location:66 → 498
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038643644.1 → XP_038499572.1  cytochrome P450 7B1 isoform X2

    Conserved Domains (1) summary
    cl41757
    Location:45 → 477
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_038643646.1 → XP_038499574.1  cytochrome P450 7B1 isoform X4

    Conserved Domains (1) summary
    cl41757
    Location:1 → 399
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  4. XM_038643645.1 → XP_038499573.1  cytochrome P450 7B1 isoform X3

    Conserved Domains (1) summary
    cl41757
    Location:66 → 407
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    14932049..15106453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579396.1 → XP_038435324.1  cytochrome P450 7B1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RK05, A0A8P0N9M7
    Conserved Domains (1) summary
    cl41757
    Location:66 → 498
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038579397.1 → XP_038435325.1  cytochrome P450 7B1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NFX8, A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:45 → 477
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_038579399.1 → XP_038435327.1  cytochrome P450 7B1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:1 → 399
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  4. XM_038579398.1 → XP_038435326.1  cytochrome P450 7B1 isoform X3

    Conserved Domains (1) summary
    cl41757
    Location:66 → 407
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    14762658..14936799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005638017.4 → XP_005638074.1  cytochrome P450 7B1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RK05, A0A8P0N9M7
    Conserved Domains (1) summary
    cl41757
    Location:66 → 498
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_022412440.2 → XP_022268148.1  cytochrome P450 7B1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NFX8, A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:45 → 477
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  3. XM_005638019.3 → XP_005638076.1  cytochrome P450 7B1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R1V1
    Conserved Domains (1) summary
    cl41757
    Location:1 → 399
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  4. XM_038460863.1 → XP_038316791.1  cytochrome P450 7B1 isoform X3

    Conserved Domains (1) summary
    cl41757
    Location:66 → 407
    cytochrome_P450; cytochrome P450 (CYP) superfamily
Nucleotide Protein
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