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CYP7A1 cytochrome P450 family 7 subfamily A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 486962, updated on 5-Mar-2024

Summary

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Official Symbol
CYP7A1provided by VGNC
Official Full Name
cytochrome P450 family 7 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:50378
See related
Ensembl:ENSCAFG00845027730
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 29
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (9370713..9397915, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (9598242..9625248, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (9773555..9801001, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (9368643..9395863, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (9494537..9521733, complement)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866668 Neighboring gene UBX domain protein 2B Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene syndecan binding protein Neighboring gene neutral sphingomyelinase activation associated factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol 7-alpha-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cholesterol 7-alpha-monooxygenase; cytochrome P450 7A1
Names
cytochrome P450, family 7, subfamily A, polypeptide 1
XP_038297144.1
XP_038297145.1
XP_038297146.1
XP_038316784.1
XP_038316785.1
XP_038371720.1
XP_038371721.1
XP_038371722.1
XP_038435289.1
XP_038435290.1
XP_038435291.1
XP_038499530.1
XP_038499531.1
XP_038499532.1
XP_544091.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    9370713..9397915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441218.1 → XP_038297146.1  cytochrome P450 7A1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SRX9
    Related
    ENSCAFP00845038394.1, ENSCAFT00845048943.1
    Conserved Domains (1) summary
    cd20631
    Location:27 → 466
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  2. XM_038441217.1 → XP_038297145.1  cytochrome P450 7A1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NML0, A0A8C0SU05, A0A8I3PV16
    Related
    ENSCAFP00845038555.1, ENSCAFT00845048983.1
    Conserved Domains (1) summary
    cd20631
    Location:52 → 491
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  3. XM_038441216.1 → XP_038297144.1  cytochrome P450 7A1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSE1, A0A8C0NRH2, A0A8C0SS44, A0A8I3PVJ4
    Related
    ENSCAFP00845038599.1, ENSCAFT00845049191.1
    Conserved Domains (1) summary
    cd20631
    Location:55 → 494
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    9368643..9395863 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515794.1 → XP_038371722.1  cytochrome P450 7A1 isoform X3

    Conserved Domains (1) summary
    cd20631
    Location:27 → 466
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  2. XM_038515793.1 → XP_038371721.1  cytochrome P450 7A1 isoform X2

    Conserved Domains (1) summary
    cd20631
    Location:52 → 491
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  3. XM_038515792.1 → XP_038371720.1  cytochrome P450 7A1 isoform X1

    Conserved Domains (1) summary
    cd20631
    Location:55 → 494
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    9494537..9521733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643604.1 → XP_038499532.1  cytochrome P450 7A1 isoform X3

    Conserved Domains (1) summary
    cd20631
    Location:27 → 466
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  2. XM_038643603.1 → XP_038499531.1  cytochrome P450 7A1 isoform X2

    Conserved Domains (1) summary
    cd20631
    Location:52 → 491
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  3. XM_038643602.1 → XP_038499530.1  cytochrome P450 7A1 isoform X1

    Conserved Domains (1) summary
    cd20631
    Location:55 → 494
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    9773555..9801001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579363.1 → XP_038435291.1  cytochrome P450 7A1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SRX9
    Conserved Domains (1) summary
    cd20631
    Location:27 → 466
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  2. XM_038579362.1 → XP_038435290.1  cytochrome P450 7A1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NML0, A0A8C0SU05, A0A8I3PV16
    Conserved Domains (1) summary
    cd20631
    Location:52 → 491
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  3. XM_038579361.1 → XP_038435289.1  cytochrome P450 7A1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSE1, A0A8C0NRH2, A0A8C0SS44, A0A8I3PVJ4
    Conserved Domains (1) summary
    cd20631
    Location:55 → 494
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    9598242..9625248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460857.1 → XP_038316785.1  cytochrome P450 7A1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SRX9
    Conserved Domains (1) summary
    cd20631
    Location:27 → 466
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  2. XM_038460856.1 → XP_038316784.1  cytochrome P450 7A1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NML0, A0A8C0SU05, A0A8I3PV16
    Conserved Domains (1) summary
    cd20631
    Location:52 → 491
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1

  3. XM_544091.5 → XP_544091.1  cytochrome P450 7A1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSE1, A0A8C0NRH2, A0A8C0SS44, A0A8I3PVJ4
    Conserved Domains (1) summary
    cd20631
    Location:55 → 494
    CYP7A1; cytochrome P450 family 7, subfamily A, polypeptide 1
Nucleotide Protein
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