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DOCK1 dedicator of cytokinesis 1 [ Canis lupus familiaris (dog) ]

Gene ID: 486934, updated on 5-Mar-2024

Summary

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Official Symbol
DOCK1provided by VGNC
Official Full Name
dedicator of cytokinesis 1provided by VGNC
Primary source
VGNC:VGNC:40043
See related
Ensembl:ENSCAFG00845027604
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 28
Exon count:
52
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (36536271..37030199)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (35960163..36453573)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (36265344..36759122)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (36012508..36505888)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (36009501..36504114)

Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092957 Neighboring gene uncharacterized LOC119866536 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111092956 Neighboring gene uncharacterized LOC119866619 Neighboring gene inhibitory synaptic factor 2A Neighboring gene uncharacterized LOC119866537 Neighboring gene neuropeptide S

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dedicator of cytokinesis protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051832.1 Reference ROS_Cfam_1.0

    Range
    36536271..37030199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038440917.1 → XP_038296845.1  dedicator of cytokinesis protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PKZ4, A0A8I3S6D8, A0A8P0NEX7
    Related
    ENSCAFP00845038213.1, ENSCAFT00845048707.1
    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_038440918.1 → XP_038296846.1  dedicator of cytokinesis protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3S6D8, A0A8P0NEX7
    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049288.1 Alternate UMICH_Zoey_3.1

    Range
    36012508..36505888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515514.1 → XP_038371442.1  dedicator of cytokinesis protein 1 isoform X1

    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_038515515.1 → XP_038371443.1  dedicator of cytokinesis protein 1 isoform X2

    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

    Range
    36009501..36504114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643341.1 → XP_038499269.1  dedicator of cytokinesis protein 1 isoform X1

    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_038643342.1 → XP_038499270.1  dedicator of cytokinesis protein 1 isoform X2

    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

    Range
    36265344..36759122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579104.1 → XP_038435032.1  dedicator of cytokinesis protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PKZ4, A0A8I3S6D8, A0A8P0NEX7
    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_038579105.1 → XP_038435033.1  dedicator of cytokinesis protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3S6D8, A0A8P0NEX7
    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35960163..36453573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460717.1 → XP_038316645.1  dedicator of cytokinesis protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PKZ4, A0A8I3S6D8, A0A8P0NEX7
    Conserved Domains (4) summary
    cd08694
    Location:445 → 640
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1235 → 1633
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 437
    DOCK_N; DOCK N-terminus

  2. XM_038460718.1 → XP_038316646.1  dedicator of cytokinesis protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3S6D8, A0A8P0NEX7
    Conserved Domains (4) summary
    cd08694
    Location:424 → 619
    C2_Dock-A; C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
    cd11707
    Location:1214 → 1612
    DHR2_DOCK1; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1
    cd12051
    Location:13 → 68
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:72 → 416
    DOCK_N; DOCK N-terminus
Nucleotide Protein
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