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PTPN6 protein tyrosine phosphatase non-receptor type 6 [ Canis lupus familiaris (dog) ]

Gene ID: 486717, updated on 5-Mar-2024

Summary

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Official Symbol
PTPN6provided by VGNC
Official Full Name
protein tyrosine phosphatase non-receptor type 6provided by VGNC
Primary source
VGNC:VGNC:45179
See related
Ensembl:ENSCAFG00845026107
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
DRPLA
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (38437567..38449584, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (8519708..8531714)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (7998465..8010486)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (38312457..38324047, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (38353429..38365020, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866430 Neighboring gene microRNA mir-200c Neighboring gene microRNA mir-141 Neighboring gene chromosome 27 C12orf57 homolog Neighboring gene uncharacterized LOC111092761 Neighboring gene U7 small nuclear RNA Neighboring gene atrophin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein phosphatase non-receptor type 6
Names
dentatorubro-pallidoluysian atrophy protein
XP_005637268.1
XP_038295067.1
XP_038369729.1
XP_038432565.1
XP_038497568.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    38437567..38449584 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038439139.1 → XP_038295067.1  tyrosine-protein phosphatase non-receptor type 6

    UniProtKB/TrEMBL
    A0A8C0JNN8, A0A8C0JRA1, A0A8C0TL66, A0A8I3S5S9
    Related
    ENSCAFP00845036300.1, ENSCAFT00845046226.1
    Conserved Domains (3) summary
    cd09931
    Location:109 → 215
    SH2_C-SH2_SHP_like; C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd10340
    Location:3 → 101
    SH2_N-SH2_SHP_like; N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd14606
    Location:253 → 518
    PTPc-N6; catalytic domain of tyrosine-protein phosphatase non-receptor type 6

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    38312457..38324047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038513801.1 → XP_038369729.1  tyrosine-protein phosphatase non-receptor type 6

    Conserved Domains (3) summary
    cd09931
    Location:109 → 215
    SH2_C-SH2_SHP_like; C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd10340
    Location:3 → 101
    SH2_N-SH2_SHP_like; N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd14606
    Location:253 → 518
    PTPc-N6; catalytic domain of tyrosine-protein phosphatase non-receptor type 6

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    38353429..38365020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038641640.1 → XP_038497568.1  tyrosine-protein phosphatase non-receptor type 6

    Conserved Domains (3) summary
    cd09931
    Location:109 → 215
    SH2_C-SH2_SHP_like; C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd10340
    Location:3 → 101
    SH2_N-SH2_SHP_like; N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd14606
    Location:253 → 518
    PTPc-N6; catalytic domain of tyrosine-protein phosphatase non-receptor type 6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    7998465..8010486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038576637.1 → XP_038432565.1  tyrosine-protein phosphatase non-receptor type 6

    UniProtKB/TrEMBL
    A0A8C0JNN8, A0A8C0JRA1, A0A8C0TL66, A0A8I3S5S9
    Conserved Domains (3) summary
    cd09931
    Location:109 → 215
    SH2_C-SH2_SHP_like; C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd10340
    Location:3 → 101
    SH2_N-SH2_SHP_like; N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd14606
    Location:253 → 518
    PTPc-N6; catalytic domain of tyrosine-protein phosphatase non-receptor type 6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8519708..8531714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005637211.4 → XP_005637268.1  tyrosine-protein phosphatase non-receptor type 6

    UniProtKB/TrEMBL
    A0A8C0JNN8, A0A8C0JRA1, A0A8C0TL66, A0A8I3S5S9
    Conserved Domains (3) summary
    cd09931
    Location:109 → 215
    SH2_C-SH2_SHP_like; C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd10340
    Location:3 → 101
    SH2_N-SH2_SHP_like; N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins
    cd14606
    Location:253 → 518
    PTPc-N6; catalytic domain of tyrosine-protein phosphatase non-receptor type 6
Nucleotide Protein
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