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VDR vitamin D receptor [ Canis lupus familiaris (dog) ]

Gene ID: 486588, updated on 5-Mar-2024

Summary

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Official Symbol
VDRprovided by VGNC
Official Full Name
vitamin D receptorprovided by VGNC
Primary source
VGNC:VGNC:48249
See related
Ensembl:ENSCAFG00845024745
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (6920266..6976964)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (39397549..39454181, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (39686018..39742660, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (6857514..6914062)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (6892693..6949518)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 106C Neighboring gene uncharacterized LOC119866303 Neighboring gene uncharacterized LOC111092909 Neighboring gene uncharacterized LOC119863949 Neighboring gene histone deacetylase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vitamin D receptor (VDR) expression in different molecular subtypes of canine mammary carcinoma. Sánchez-Céspedes R, et al. BMC Vet Res, 2021 May 25. PMID 34034728, Free PMC Article
  2. An immunohistochemical study of vitamin D receptor expression in canine cutaneous mast cell tumours. Russell DS, et al. J Comp Pathol, 2010 Aug-Oct. PMID 20334872

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Vitamin D receptor (VDR) expression in different molecular subtypes of canine mammary carcinoma.
    Title: Vitamin D receptor (VDR) expression in different molecular subtypes of canine mammary carcinoma.
  2. VDR is widely expressed by reactive and neoplastic canine mast cells in vivo.
    Title: An immunohistochemical study of vitamin D receptor expression in canine cutaneous mast cell tumours.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vitamin D response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vitamin D3 receptor; LOW QUALITY PROTEIN: vitamin D3 receptor
Names
vitamin D (1,25- dihydroxyvitamin D3) receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    6920266..6976964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438367.1 → XP_038294295.1  vitamin D3 receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBF2, A0A8C0PAI2, A0A8C0T3I0, A0A8I3PNH6
    Related
    ENSCAFP00845034217.1, ENSCAFT00845043675.1
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    6857514..6914062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038513076.1 → XP_038369004.1  vitamin D3 receptor isoform X2

  2. XM_038513077.1 → XP_038369005.1  vitamin D3 receptor isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    6892693..6949518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640838.1 → XP_038496766.1  vitamin D3 receptor isoform X1

    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    39686018..39742660 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577464.1 → XP_038433392.1  LOW QUALITY PROTEIN: vitamin D3 receptor isoform X4

    UniProtKB/TrEMBL
    A0A8C0T3I0

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39397549..39454181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460039.1 → XP_038315967.1  vitamin D3 receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0KBF2, A0A8C0PAI2, A0A8C0T3I0, A0A8I3PNH6
    Conserved Domains (2) summary
    cd06933
    Location:124 → 426
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16 → 122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers
Nucleotide Protein
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