CYP24A1 cytochrome P450 family 24 subfamily A member 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: CYP24A1provided by VGNC
Official Full Name: cytochrome P450 family 24 subfamily A member 1provided by VGNC
Primary source: VGNC:VGNC:50338
See related: Ensembl:ENSCAFG00845028958
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	24	NC_051828.1 (40574274..40591063, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	24	NC_006606.4 (39106835..39123588, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	24	NC_049245.1 (40527730..40544495, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	24	NC_049284.1 (39809842..39826569, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	24	NC_049765.1 (39945173..39961923, complement)

Chromosome 24 - NC_051828.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in C21-steroid hormone biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to peptide hormone stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cortisol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glucocorticoid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Names: cytochrome P450, family 24, subfamily A, polypeptide 1

XP_038290049.1

EC 1.14.15.16

XP_038365218.1

EC 1.14.15.16

XP_038428558.1

EC 1.14.15.16

XP_038492830.1

EC 1.14.15.16

XP_543059.2

EC 1.14.15.16

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051828.1 Reference ROS_Cfam_1.0

Range

40574274..40591063 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038434121.1 → XP_038290049.1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

UniProtKB/TrEMBL

A0A8C0LB28, A0A8C0LCR0, A0A8C0SJU9, A0A8I3PYQ1

Related

ENSCAFP00845040217.1, ENSCAFT00845051276.1

Conserved Domains (1) summary

cd20645
Location:90 → 508

CYP24A1; cytochrome P450 family 24, subfamily A, polypeptide 1, also called vitamin D(3) 24-hydroxylase

Alternate UMICH_Zoey_3.1

Genomic

NC_049284.1 Alternate UMICH_Zoey_3.1

Range

39809842..39826569 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038509290.1 → XP_038365218.1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Conserved Domains (1) summary

cd20645
Location:90 → 508

CYP24A1; cytochrome P450 family 24, subfamily A, polypeptide 1, also called vitamin D(3) 24-hydroxylase

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049765.1 Alternate UNSW_CanFamBas_1.0

Range

39945173..39961923 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038636902.1 → XP_038492830.1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Conserved Domains (1) summary

cd20645
Location:90 → 508

CYP24A1; cytochrome P450 family 24, subfamily A, polypeptide 1, also called vitamin D(3) 24-hydroxylase

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049245.1 Alternate UU_Cfam_GSD_1.0

Range

40527730..40544495 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038572630.1 → XP_038428558.1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

UniProtKB/TrEMBL

A0A8C0LB28, A0A8C0LCR0, A0A8C0SJU9, A0A8I3PYQ1

Conserved Domains (1) summary

cd20645
Location:90 → 508

CYP24A1; cytochrome P450 family 24, subfamily A, polypeptide 1, also called vitamin D(3) 24-hydroxylase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

39106835..39123588 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_543059.5 → XP_543059.2 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

UniProtKB/TrEMBL

A0A8C0LCR0, A0A8P0NE13

Conserved Domains (1) summary

pfam00067
Location:59 → 509

p450; Cytochrome P450