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E2F1 E2F transcription factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 485839, updated on 5-Mar-2024

Summary

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Gene symbol
E2F1
Gene description
E2F transcription factor 1
See related
Ensembl:ENSCAFG00845025182
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See E2F1 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (23581877..23591392, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (22540395..22549906, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (23399012..23408523, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (22874367..22883878, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (22967923..22977434, complement)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene CBFA2/RUNX1 partner transcriptional co-repressor 2 Neighboring gene uncharacterized LOC111092231 Neighboring gene N-terminal EF-hand calcium binding protein 3 Neighboring gene actin like 10 Neighboring gene U6 spliceosomal RNA Neighboring gene mitochondrial import inner membrane translocase subunit Tim8 A Neighboring gene peroxisomal membrane protein 4 Neighboring gene zinc finger protein 341

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Rb-E2F complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor E2F1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    23581877..23591392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433535.1 → XP_038289463.1  transcription factor E2F1

    UniProtKB/TrEMBL
    A0A8C0JV99, A0A8C0Q8Y6, A0A8I3PK29
    Related
    ENSCAFP00845034906.1, ENSCAFT00845044551.1
    Conserved Domains (2) summary
    cd14660
    Location:202 → 301
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:129 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    22874367..22883878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508717.1 → XP_038364645.1  transcription factor E2F1

    Conserved Domains (2) summary
    cd14660
    Location:202 → 301
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:129 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    22967923..22977434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038636281.1 → XP_038492209.1  transcription factor E2F1

    Conserved Domains (2) summary
    cd14660
    Location:202 → 301
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:129 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    23399012..23408523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038572031.1 → XP_038427959.1  transcription factor E2F1

    UniProtKB/TrEMBL
    A0A8C0JV99, A0A8C0Q8Y6, A0A8I3PK29
    Conserved Domains (2) summary
    cd14660
    Location:202 → 301
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:129 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    22540395..22549906 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005634945.3 → XP_005635002.1  transcription factor E2F1

    UniProtKB/TrEMBL
    A0A8C0JV99, A0A8C0Q8Y6, A0A8I3PK29
    Conserved Domains (2) summary
    cd14660
    Location:202 → 301
    E2F_DD; Dimerization domain of E2F transcription factors
    pfam02319
    Location:129 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
Nucleotide Protein
Heading Accession and Version

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