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CYP8B1 cytochrome P450 family 8 subfamily B member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 485619, updated on 5-Mar-2024

Summary

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Official Symbol
CYP8B1provided by VGNC
Official Full Name
cytochrome P450 family 8 subfamily B member 1provided by VGNC
Primary source
VGNC:VGNC:50380
See related
Ensembl:ENSCAFG00845021247
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
1
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (12255398..12258673, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (11939545..11942820, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (12202997..12206280, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (12057378..12060653, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (12199554..12202829, complement)

Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 pseudogene Neighboring gene HIG1 hypoxia inducible domain family member 1A Neighboring gene atypical chemokine receptor 2 Neighboring gene zinc finger protein 662 Neighboring gene golgi associated kinase 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sterol 12-alpha-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; LOW QUALITY PROTEIN: 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051827.1 Reference ROS_Cfam_1.0

    Range
    12255398..12258673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038432041.1 → XP_038287969.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0Z062, A0A8I3PFY5
    Related
    ENSCAFP00845029367.1, ENSCAFT00845037483.1
    Conserved Domains (1) summary
    cl41757
    Location:57 → 493
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049283.1 Alternate UMICH_Zoey_3.1

    Range
    12057378..12060653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038507349.1 → XP_038363277.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    Conserved Domains (1) summary
    cl41757
    Location:57 → 493
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

    Range
    12199554..12202829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634769.1 → XP_038490697.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    Conserved Domains (1) summary
    cl41757
    Location:57 → 493
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

    Range
    12202997..12206280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570587.1 → XP_038426515.1  LOW QUALITY PROTEIN: 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0Z062, A0A8I3PFY5
    Conserved Domains (1) summary
    cl41757
    Location:57 → 493
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11939545..11942820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005634313.4 → XP_005634370.1  5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase

    UniProtKB/TrEMBL
    A0A8C0LND4, A0A8C0NR21, A0A8P0N817
    Conserved Domains (1) summary
    cl12078
    Location:38 → 493
    p450; Cytochrome P450
Nucleotide Protein
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