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SPRY2 sprouty RTK signaling antagonist 2 [ Canis lupus familiaris (dog) ]

Gene ID: 485504, updated on 5-Mar-2024

Summary

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Official Symbol
SPRY2provided by VGNC
Official Full Name
sprouty RTK signaling antagonist 2provided by VGNC
Primary source
VGNC:VGNC:46766
See related
Ensembl:ENSCAFG00845028431
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
2
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (33695480..33700592, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (33168781..33173903, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (33464090..33469216, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (33352773..33357889, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (33390454..33395571, complement)

Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865143 Neighboring gene uncharacterized LOC106557558 Neighboring gene uncharacterized LOC111091753 Neighboring gene 60S ribosomal protein L27-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein sprouty homolog 2
Names
sprouty homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051826.1 Reference ROS_Cfam_1.0

    Range
    33695480..33700592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431272.1 → XP_038287200.1  protein sprouty homolog 2

    UniProtKB/TrEMBL
    A0A8C0LDM5, A0A8C0RCA5, A0A8I3PYH2
    Related
    ENSCAFP00845039337.1, ENSCAFT00845050169.1
    Conserved Domains (1) summary
    pfam05210
    Location:183 → 284
    Sprouty; Sprouty protein (Spry)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049282.1 Alternate UMICH_Zoey_3.1

    Range
    33352773..33357889 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038506656.1 → XP_038362584.1  protein sprouty homolog 2

    Conserved Domains (1) summary
    pfam05210
    Location:183 → 284
    Sprouty; Sprouty protein (Spry)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

    Range
    33390454..33395571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634010.1 → XP_038489938.1  protein sprouty homolog 2

    Conserved Domains (1) summary
    pfam05210
    Location:183 → 284
    Sprouty; Sprouty protein (Spry)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

    Range
    33464090..33469216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038569857.1 → XP_038425785.1  protein sprouty homolog 2

    UniProtKB/TrEMBL
    A0A8C0LDM5, A0A8C0RCA5, A0A8I3PYH2
    Conserved Domains (1) summary
    pfam05210
    Location:183 → 284
    Sprouty; Sprouty protein (Spry)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    33168781..33173903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003433059.5 → XP_003433107.1  protein sprouty homolog 2

    See identical proteins and their annotated locations for XP_003433107.1

    UniProtKB/TrEMBL
    A0A8C0LDM5, A0A8C0RCA5, A0A8I3PYH2
    Conserved Domains (1) summary
    pfam05210
    Location:183 → 284
    Sprouty; Sprouty protein (Spry)
Nucleotide Protein
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