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MAML2 mastermind like transcriptional coactivator 2 [ Canis lupus familiaris (dog) ]

Gene ID: 485116, updated on 5-Mar-2024

Summary

Official Symbol
MAML2provided by VGNC
Official Full Name
mastermind like transcriptional coactivator 2provided by VGNC
Primary source
VGNC:VGNC:42940
See related
Ensembl:ENSCAFG00845017403
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (4994635..5339158)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (4835079..5178107)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (4902938..5245712)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (4783514..5136428)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (4855134..5198035)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 82 Neighboring gene JRK like Neighboring gene 40S ribosomal protein S2-like Neighboring gene uncharacterized LOC111091477 Neighboring gene uncharacterized LOC119864942 Neighboring gene uncharacterized LOC119864941 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene uncharacterized LOC106560166 Neighboring gene myotubularin related protein 2 Neighboring gene centrosomal protein 57

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of transcription of Notch receptor target IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
mastermind-like protein 2; LOW QUALITY PROTEIN: mastermind-like protein 2
Names
mastermind-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    4994635..5339158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429689.1XP_038285617.1  mastermind-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6
    Related
    ENSCAFP00845024183.1, ENSCAFT00845030849.1
    Conserved Domains (2) summary
    PRK07764
    Location:369488
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam09596
    Location:3188
    MamL-1; MamL-1 domain
  2. XM_038429690.1XP_038285618.1  mastermind-like protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6
    Conserved Domains (2) summary
    PRK07764
    Location:369488
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam09596
    Location:3188
    MamL-1; MamL-1 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    4783514..5136428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505107.1XP_038361035.1  LOW QUALITY PROTEIN: mastermind-like protein 2 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    4855134..5198035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038632368.1XP_038488296.1  mastermind-like protein 2 isoform X1

  2. XM_038632369.1XP_038488297.1  mastermind-like protein 2 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    4902938..5245712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568227.1XP_038424155.1  mastermind-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6
  2. XM_038568228.1XP_038424156.1  mastermind-like protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4835079..5178107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_542234.7XP_542234.3  mastermind-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6
    Conserved Domains (2) summary
    PRK07764
    Location:369486
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam09596
    Location:3188
    MamL-1; MamL-1 domain
  2. XM_022407462.2XP_022263170.2  mastermind-like protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NXM7, A0A8P0S9L6
    Conserved Domains (2) summary
    PRK07764
    Location:369486
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam09596
    Location:3188
    MamL-1; MamL-1 domain