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PIAS4 protein inhibitor of activated STAT 4 [ Canis lupus familiaris (dog) ]

Gene ID: 485049, updated on 5-Mar-2024

Summary

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Official Symbol
PIAS4provided by VGNC
Official Full Name
protein inhibitor of activated STAT 4provided by VGNC
Primary source
VGNC:VGNC:44522
See related
Ensembl:ENSCAFG00845006856
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (56189988..56213507, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (55255747..55279377, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (55926678..55950158, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (55246339..55269941, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (55727726..55751327, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864778 Neighboring gene translation initiation factor IF-2-like Neighboring gene basic salivary proline-rich protein 4-like Neighboring gene zinc finger and BTB domain containing 7A Neighboring gene small nucleolar RNA SNORD37 Neighboring gene eukaryotic translation elongation factor 2 Neighboring gene death associated protein kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SUMO ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein sumoylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 SUMO-protein ligase PIAS4
XP_022262932.1
XP_038285030.1
XP_038285031.1
XP_038285032.1
XP_038311314.1
XP_038360603.1
XP_038360604.1
XP_038360605.1
XP_038423702.1
XP_038423703.1
XP_038423704.1
XP_038487827.1
XP_038487828.1
XP_038487829.1
XP_542167.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    56189988..56213507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429103.1 → XP_038285031.1  E3 SUMO-protein ligase PIAS4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QIF7, A0A8C0R3L2, A0A8I3N076, A0A8I3N491, A0A8P0TLG5
    Related
    ENSCAFP00845009559.1, ENSCAFT00845012227.1
    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:132 → 276
    PINIT; PINIT domain

  2. XM_038429104.1 → XP_038285032.1  E3 SUMO-protein ligase PIAS4 isoform X3

    UniProtKB/TrEMBL
    A0A8I3N491, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:313 → 360
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:122 → 266
    PINIT; PINIT domain

  3. XM_038429102.1 → XP_038285030.1  E3 SUMO-protein ligase PIAS4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZ78, A0A8I3N491, A0A8P0NKH1, A0A8P0TLG5
    Related
    ENSCAFP00845009594.1, ENSCAFT00845012274.1
    Conserved Domains (3) summary
    smart00513
    Location:18 → 52
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:329 → 376
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:138 → 282
    PINIT; PINIT domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    55246339..55269941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504676.1 → XP_038360604.1  E3 SUMO-protein ligase PIAS4 isoform X2

    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:132 → 276
    PINIT; PINIT domain

  2. XM_038504677.1 → XP_038360605.1  E3 SUMO-protein ligase PIAS4 isoform X3

    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:313 → 360
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:122 → 266
    PINIT; PINIT domain

  3. XM_038504675.1 → XP_038360603.1  E3 SUMO-protein ligase PIAS4 isoform X1

    Conserved Domains (3) summary
    smart00513
    Location:18 → 52
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:329 → 376
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:138 → 282
    PINIT; PINIT domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    55727726..55751327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631900.1 → XP_038487828.1  E3 SUMO-protein ligase PIAS4 isoform X2

    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:132 → 276
    PINIT; PINIT domain

  2. XM_038631901.1 → XP_038487829.1  E3 SUMO-protein ligase PIAS4 isoform X3

    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:313 → 360
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:122 → 266
    PINIT; PINIT domain

  3. XM_038631899.1 → XP_038487827.1  E3 SUMO-protein ligase PIAS4 isoform X1

    Conserved Domains (3) summary
    smart00513
    Location:18 → 52
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:329 → 376
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:138 → 282
    PINIT; PINIT domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    55926678..55950158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567775.1 → XP_038423703.1  E3 SUMO-protein ligase PIAS4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QIF7, A0A8C0R3L2, A0A8I3N076, A0A8I3N491, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:132 → 276
    PINIT; PINIT domain

  2. XM_038567776.1 → XP_038423704.1  E3 SUMO-protein ligase PIAS4 isoform X3

    UniProtKB/TrEMBL
    A0A8I3N491, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:313 → 360
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:122 → 266
    PINIT; PINIT domain

  3. XM_038567774.1 → XP_038423702.1  E3 SUMO-protein ligase PIAS4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZ78, A0A8I3N491, A0A8P0NKH1, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:18 → 52
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:329 → 376
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:138 → 282
    PINIT; PINIT domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    55255747..55279377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_542167.8 → XP_542167.4  E3 SUMO-protein ligase PIAS4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QIF7, A0A8C0R3L2, A0A8I3N076, A0A8I3N491, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:323 → 370
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:132 → 276
    PINIT; PINIT domain

  2. XM_022407224.2 → XP_022262932.1  E3 SUMO-protein ligase PIAS4 isoform X3

    UniProtKB/TrEMBL
    A0A8I3N491, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:313 → 360
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:122 → 266
    PINIT; PINIT domain

  3. XM_038455386.1 → XP_038311314.1  E3 SUMO-protein ligase PIAS4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MZ78, A0A8I3N491, A0A8P0NKH1, A0A8P0TLG5
    Conserved Domains (3) summary
    smart00513
    Location:18 → 52
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:329 → 376
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:138 → 282
    PINIT; PINIT domain
Nucleotide Protein
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