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CDC25A cell division cycle 25A [ Canis lupus familiaris (dog) ]

Gene ID: 484780, updated on 5-Mar-2024

Summary

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Official Symbol
CDC25Aprovided by VGNC
Official Full Name
cell division cycle 25Aprovided by VGNC
Primary source
VGNC:VGNC:38989
See related
Ensembl:ENSCAFG00845007301
Gene type
protein coding
RefSeq status
INFERRED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (41309415..41334896)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (40741248..40764940)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (41231962..41255400)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (40549928..40573619)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (40951503..40974658)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091448 Neighboring gene cathelicidin antimicrobial peptide Neighboring gene microtubule associated protein 4 Neighboring gene short transmembrane mitochondrial protein 1-like Neighboring gene DExH-box helicase 30

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of G2/MI transition of meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
M-phase inducer phosphatase 1
Names
cell division cycle 25 homolog A
NP_001138687.1
XP_038282385.1
XP_038282386.1
XP_038282387.1
XP_038282388.1
XP_038282389.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145215.1 → NP_001138687.1  M-phase inducer phosphatase 1

    Status: INFERRED

    Source sequence(s)
    JAAUVH010000291
    UniProtKB/TrEMBL
    A0A8C0L862, A0A8C0TR13, A0A8I3RVA5
    Related
    ENSCAFP00845010052.1, ENSCAFT00845012898.1
    Conserved Domains (2) summary
    cd01530
    Location:357 → 474
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85 → 328
    M-inducer_phosp; M-phase inducer phosphatase

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    41309415..41334896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426460.1 → XP_038282388.1  M-phase inducer phosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L7D1
    Conserved Domains (2) summary
    COG5105
    Location:115 → 398
    MIH1; Mitotic inducer, protein phosphatase [Cell division and chromosome partitioning]
    cd01530
    Location:247 → 364
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...

  2. XM_038426461.1 → XP_038282389.1  M-phase inducer phosphatase 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L7D1
    Conserved Domains (2) summary
    COG5105
    Location:114 → 397
    MIH1; Mitotic inducer, protein phosphatase [Cell division and chromosome partitioning]
    cd01530
    Location:246 → 363
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...

  3. XM_038426458.1 → XP_038282386.1  M-phase inducer phosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L7D1, A0A8C0P1W4, A0A8I3N5L5
    Related
    ENSCAFP00845010138.1, ENSCAFT00845013011.1
    Conserved Domains (2) summary
    cd01530
    Location:317 → 434
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85 → 288
    M-inducer_phosp; M-phase inducer phosphatase

  4. XM_038426459.1 → XP_038282387.1  M-phase inducer phosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L7D1
    Conserved Domains (2) summary
    cd01530
    Location:316 → 433
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85 → 287
    M-inducer_phosp; M-phase inducer phosphatase

  5. XM_038426457.1 → XP_038282385.1  M-phase inducer phosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L862
    Conserved Domains (2) summary
    cd01530
    Location:356 → 473
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85 → 327
    M-inducer_phosp; M-phase inducer phosphatase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    40549928..40573619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    40951503..40974658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    41231962..41255400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    40741248..40764940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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