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MAPKAPK3 MAPK activated protein kinase 3 [ Canis lupus familiaris (dog) ]

Gene ID: 484756, updated on 5-Mar-2024

Summary

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Official Symbol
MAPKAPK3provided by VGNC
Official Full Name
MAPK activated protein kinase 3provided by VGNC
Primary source
VGNC:VGNC:43007
See related
Ensembl:ENSCAFG00845020171
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (39084740..39112355, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (38649808..38677437, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (39136177..39163793, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (38452657..38480274, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (38856269..38883882, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 3 Neighboring gene cofilin-1-like Neighboring gene eukaryotic initiation factor 4A-I-like Neighboring gene uncharacterized LOC102152043 Neighboring gene cytokine inducible SH2 containing protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MAP kinase-activated protein kinase 3; LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 3
Names
mitogen-activated protein kinase-activated protein kinase 3
XP_038283577.1
XP_038283578.1
XP_038283579.1
XP_038283580.1
XP_038283581.1
XP_038311315.1
XP_038359268.1
XP_038422263.1
XP_038422264.1
XP_038422265.1
XP_038422266.1
XP_038422267.1
XP_038486419.1
XP_038486420.1
XP_541872.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    39084740..39112355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427650.1 → XP_038283578.1  MAP kinase-activated protein kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCG0, A0A8C0MYY8, A0A8C0SLN3, A0A8I3S4A4
    Related
    ENSCAFP00845027796.1, ENSCAFT00845035530.1
    Conserved Domains (1) summary
    cd14172
    Location:38 → 303
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

  2. XM_038427649.1 → XP_038283577.1  MAP kinase-activated protein kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L821, A0A8C0SLN3, A0A8I3P736
    Related
    ENSCAFP00845027947.1, ENSCAFT00845035720.1
    Conserved Domains (1) summary
    cl21453
    Location:38 → 344
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038427651.1 → XP_038283579.1  MAP kinase-activated protein kinase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SLN3
    Conserved Domains (1) summary
    cd14089
    Location:50 → 280
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

  4. XM_038427652.1 → XP_038283580.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0R5S5, A0A8C0SLN3, A0A8I3PBZ6
    Related
    ENSCAFP00845027852.1, ENSCAFT00845035604.1
    Conserved Domains (1) summary
    cd14089
    Location:37 → 268
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

  5. XM_038427653.1 → XP_038283581.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0R5S5, A0A8C0SLN3, A0A8I3PBZ6
    Conserved Domains (1) summary
    cd14089
    Location:37 → 268
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    38452657..38480274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503340.1 → XP_038359268.1  LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 3 isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    38856269..38883882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630491.1 → XP_038486419.1  MAP kinase-activated protein kinase 3 isoform X3

  2. XM_038630492.1 → XP_038486420.1  MAP kinase-activated protein kinase 3 isoform X4

    Conserved Domains (1) summary
    cd14089
    Location:50 → 280
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    39136177..39163793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566336.1 → XP_038422264.1  MAP kinase-activated protein kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCG0, A0A8C0MYY8, A0A8C0SLN3, A0A8I3S4A4
    Conserved Domains (1) summary
    cd14172
    Location:38 → 303
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

  2. XM_038566335.1 → XP_038422263.1  MAP kinase-activated protein kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L821, A0A8C0SLN3, A0A8I3P736
    Conserved Domains (1) summary
    cl21453
    Location:38 → 344
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038566337.1 → XP_038422265.1  MAP kinase-activated protein kinase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SLN3
    Conserved Domains (1) summary
    cd14089
    Location:50 → 280
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

  4. XM_038566338.1 → XP_038422266.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0R5S5, A0A8C0SLN3, A0A8I3PBZ6
    Conserved Domains (1) summary
    cd14089
    Location:37 → 268
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

  5. XM_038566339.1 → XP_038422267.1  MAP kinase-activated protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0R5S5, A0A8C0SLN3, A0A8I3PBZ6
    Conserved Domains (1) summary
    cd14089
    Location:37 → 268
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38649808..38677437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_541872.6 → XP_541872.4  MAP kinase-activated protein kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LCG0, A0A8C0MYY8, A0A8C0SLN3, A0A8I3S4A4
    Conserved Domains (1) summary
    cd14172
    Location:38 → 303
    STKc_MAPKAPK3; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 3

  2. XM_038455387.1 → XP_038311315.1  MAP kinase-activated protein kinase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SLN3
    Conserved Domains (1) summary
    cd14089
    Location:50 → 280
    STKc_MAPKAPK; Catalytic domain of the Serine/Threonine kinases, Mitogen-activated protein kinase-activated protein kinases
Nucleotide Protein
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