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APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 [ Canis lupus familiaris (dog) ]

Gene ID: 484716, updated on 5-Mar-2024

Summary

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Official Symbol
APPL1provided by VGNC
Official Full Name
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1provided by VGNC
Primary source
VGNC:VGNC:38012
See related
Ensembl:ENSCAFG00845023259
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (33395990..33439031, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (33051161..33094218, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (33374797..33418067, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (32845010..32887864, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (33203498..33246471, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 12 Neighboring gene dynein axonemal heavy chain 12 Neighboring gene homeobox protein TGIF2-like Neighboring gene ankyrin repeat and SOCS box containing 14 Neighboring gene uncharacterized LOC111091307 Neighboring gene 14-3-3 protein zeta/delta-like Neighboring gene HESX homeobox 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DCC-interacting protein 13-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    33395990..33439031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427430.1 → XP_038283358.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZS5, A0A8C0JZX7, A0A8C0PHT0, A0A8I3PIV9
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_038427432.1 → XP_038283360.1  DCC-interacting protein 13-alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZX7
    Conserved Domains (3) summary
    cd13158
    Location:469 → 604
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:232 → 356
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:20 → 214
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038427429.1 → XP_038283357.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZS5, A0A8C0JZX7, A0A8C0PHT0, A0A8I3PIV9
    Related
    ENSCAFP00845032178.1, ENSCAFT00845041063.1
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  4. XM_038427433.1 → XP_038283361.1  DCC-interacting protein 13-alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:408 → 543
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:171 → 295
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:15 → 153
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_038427434.1 → XP_038283362.1  DCC-interacting protein 13-alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:379 → 514
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:142 → 266
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 124
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    32845010..32887864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503144.1 → XP_038359072.1  DCC-interacting protein 13-alpha isoform X1

    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_038503145.1 → XP_038359073.1  DCC-interacting protein 13-alpha isoform X2

    Conserved Domains (3) summary
    cd13158
    Location:469 → 604
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:232 → 356
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:20 → 214
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038503143.1 → XP_038359071.1  DCC-interacting protein 13-alpha isoform X1

    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  4. XM_038503146.1 → XP_038359074.1  DCC-interacting protein 13-alpha isoform X3

    Conserved Domains (3) summary
    cd13158
    Location:408 → 543
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:171 → 295
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:15 → 153
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_038503147.1 → XP_038359075.1  DCC-interacting protein 13-alpha isoform X4

    Conserved Domains (3) summary
    cd13158
    Location:379 → 514
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:142 → 266
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 124
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    33203498..33246471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630254.1 → XP_038486182.1  DCC-interacting protein 13-alpha isoform X1

    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_038630255.1 → XP_038486183.1  DCC-interacting protein 13-alpha isoform X2

    Conserved Domains (3) summary
    cd13158
    Location:469 → 604
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:232 → 356
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:20 → 214
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038630253.1 → XP_038486181.1  DCC-interacting protein 13-alpha isoform X1

    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  4. XM_038630256.1 → XP_038486184.1  DCC-interacting protein 13-alpha isoform X3

    Conserved Domains (3) summary
    cd13158
    Location:408 → 543
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:171 → 295
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:15 → 153
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_038630257.1 → XP_038486185.1  DCC-interacting protein 13-alpha isoform X4

    Conserved Domains (3) summary
    cd13158
    Location:379 → 514
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:142 → 266
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 124
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    33374797..33418067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566106.1 → XP_038422034.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZS5, A0A8C0JZX7, A0A8C0PHT0, A0A8I3PIV9
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_038566107.1 → XP_038422035.1  DCC-interacting protein 13-alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZX7
    Conserved Domains (3) summary
    cd13158
    Location:469 → 604
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:232 → 356
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:20 → 214
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038566105.1 → XP_038422033.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZS5, A0A8C0JZX7, A0A8C0PHT0, A0A8I3PIV9
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  4. XM_038566108.1 → XP_038422036.1  DCC-interacting protein 13-alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:408 → 543
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:171 → 295
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:15 → 153
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_038566109.1 → XP_038422037.1  DCC-interacting protein 13-alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:379 → 514
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:142 → 266
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 124
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    33051161..33094218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022406556.2 → XP_022262264.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZX7, A0A8P0NAH5
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_005632403.4 → XP_005632460.1  DCC-interacting protein 13-alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZX7
    Conserved Domains (4) summary
    cd13158
    Location:469 → 604
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:232 → 356
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    pfam00169
    Location:260 → 355
    PH; PH domain
    cl12013
    Location:20 → 214
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_843982.6 → XP_849075.1  DCC-interacting protein 13-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZX7, A0A8P0NAH5
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:489 → 624
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  4. XM_022406558.1 → XP_022262266.1  DCC-interacting protein 13-alpha isoform X3

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:408 → 543
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:171 → 295
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:15 → 153
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_022406559.2 → XP_022262267.1  DCC-interacting protein 13-alpha isoform X4

    UniProtKB/TrEMBL
    A0A8C0SMX7
    Conserved Domains (3) summary
    cd13158
    Location:379 → 514
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:142 → 266
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
    cl12013
    Location:1 → 124
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
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