DLL3 delta like canonical Notch ligand 3 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DLL3provided by VGNC
Official Full Name: delta like canonical Notch ligand 3provided by VGNC
Primary source: VGNC:VGNC:53689
See related: Ensembl:ENSCAFG00845004619
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (114338412..114346404, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (113141459..113149451, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (114525073..114533065, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (113897659..113905662, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (113530679..113538682, complement)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment or maintenance of epithelial cell apical/basal polarity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: delta-like protein 3; LOW QUALITY PROTEIN: delta-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

114338412..114346404 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038657005.1 → XP_038512933.1 delta-like protein 3

UniProtKB/TrEMBL

A0A8C0SK65, A0A8I3N977, A0A8P0TTR8

Related

ENSCAFP00845006493.1, ENSCAFT00845008259.1

Conserved Domains (4) summary

cd00054
Location:277 → 308

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

pfam00008
Location:314 → 347

EGF; EGF-like domain

pfam07657
Location:27 → 84

MNNL; N-terminus of Notch ligand

cl19567
Location:157 → 247

DSL; Delta serrate ligand

Alternate UMICH_Zoey_3.1

Genomic

NC_049261.1 Alternate UMICH_Zoey_3.1

Range

113897659..113905662 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038468156.1 → XP_038324084.1 delta-like protein 3

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049742.1 Alternate UNSW_CanFamBas_1.0

Range

113530679..113538682 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038593178.1 → XP_038449106.1 LOW QUALITY PROTEIN: delta-like protein 3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049222.1 Alternate UU_Cfam_GSD_1.0

Range

114525073..114533065 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038528906.1 → XP_038384834.1 delta-like protein 3

UniProtKB/TrEMBL

A0A8C0SK65

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

113141459..113149451 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038451709.1 → XP_038307637.1 delta-like protein 3

UniProtKB/TrEMBL

A0A8C0SK65, A0A8I3N977, A0A8P0TTR8

Conserved Domains (4) summary

cd00054
Location:277 → 308

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

pfam00008
Location:314 → 347

EGF; EGF-like domain

pfam07657
Location:27 → 84

MNNL; N-terminus of Notch ligand

cl19567
Location:157 → 247

DSL; Delta serrate ligand