GSK3A glycogen synthase kinase 3 alpha [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: GSK3Aprovided by VGNC
Official Full Name: glycogen synthase kinase 3 alphaprovided by VGNC
Primary source: VGNC:VGNC:101443
See related: Ensembl:ENSCAFG00845000891
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (112741760..112751476)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (111555288..111565002)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (112858454..112868171)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (112295962..112305677)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (111931910..111941621)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

MARC_17709-17710:1031755211:1 (e-PCR)
- UniSTS:268383

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in insulin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of TOR signaling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of neuron projection development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glycogen synthase kinase-3 alpha; LOW QUALITY PROTEIN: glycogen synthase kinase-3 alpha

XP_013972105.2

EC 2.7.11.26

XP_038323944.1

EC 2.7.11.26

XP_038384681.1

EC 2.7.11.26

XP_038448954.1

EC 2.7.11.26

XP_038512770.1

EC 2.7.11.26

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

112741760..112751476

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038656842.1 → XP_038512770.1 glycogen synthase kinase-3 alpha

UniProtKB/TrEMBL

A0A8C0KL64, A0A8C0KP76, A0A8C0M9C6, A0A8I3MIZ4

Related

ENSCAFP00845001186.1, ENSCAFT00845001508.1

Conserved Domains (1) summary

cd14137
Location:114 → 406

STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

Alternate UMICH_Zoey_3.1

Genomic

NC_049261.1 Alternate UMICH_Zoey_3.1

Range

112295962..112305677

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038468016.1 → XP_038323944.1 glycogen synthase kinase-3 alpha

Conserved Domains (1) summary

cd14137
Location:114 → 406

STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049742.1 Alternate UNSW_CanFamBas_1.0

Range

111931910..111941621

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038593026.1 → XP_038448954.1 LOW QUALITY PROTEIN: glycogen synthase kinase-3 alpha

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049222.1 Alternate UU_Cfam_GSD_1.0

Range

112858454..112868171

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038528753.1 → XP_038384681.1 glycogen synthase kinase-3 alpha

UniProtKB/TrEMBL

A0A8C0KL64, A0A8C0KP76, A0A8C0M9C6, A0A8I3MIZ4

Conserved Domains (1) summary

cd14137
Location:114 → 406

STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

111555288..111565002

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_014116630.3 → XP_013972105.2 glycogen synthase kinase-3 alpha

UniProtKB/TrEMBL

A0A8C0KL64, A0A8C0KP76, A0A8C0M9C6, A0A8I3MIZ4

Conserved Domains (1) summary

cd14137
Location:114 → 406

STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3