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PPP2R1A protein phosphatase 2 scaffold subunit Aalpha [ Canis lupus familiaris (dog) ]

Gene ID: 484335, updated on 22-Jan-2024

Summary

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Official Symbol
PPP2R1Aprovided by VGNC
Official Full Name
protein phosphatase 2 scaffold subunit Aalphaprovided by VGNC
Primary source
VGNC:VGNC:44905
See related
Ensembl:ENSCAFG00845004686
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

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Location:
chromosome: 1
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (105482896..105522584, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (104546959..104586647, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (105597164..105636892, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (105155353..105195079, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (104809802..104849707, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene vomeronasal type-1 receptor 4-like Neighboring gene vomeronasal type-1 receptor 4-like Neighboring gene 40S ribosomal protein S27-like Neighboring gene vomeronasal type-1 receptor 4-like Neighboring gene transmembrane protein 216-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein phosphatase type 2A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
XP_005616279.1
XP_038323179.1
XP_038323180.1
XP_038383886.1
XP_038383887.1
XP_038448181.1
XP_038448182.1
XP_038511969.1
XP_038511970.1
XP_850993.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    105482896..105522584 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656041.1 → XP_038511969.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVK3, A0A8C0R3W1
    Related
    ENSCAFP00845006592.1, ENSCAFT00845008378.1
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

  2. XM_038656042.1 → XP_038511970.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2

    UniProtKB/TrEMBL
    A0A8C0L2V5, A0A8C0PZQ3, A0A8I3MUF0
    Related
    ENSCAFP00845006595.1, ENSCAFT00845008382.1
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    105155353..105195079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467251.1 → XP_038323179.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

  2. XM_038467252.1 → XP_038323180.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2

    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    104809802..104849707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592253.1 → XP_038448181.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

  2. XM_038592254.1 → XP_038448182.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2

    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    105597164..105636892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038527958.1 → XP_038383886.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVK3, A0A8C0R3W1
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

  2. XM_038527959.1 → XP_038383887.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2

    UniProtKB/TrEMBL
    A0A8C0L2V5, A0A8C0PZQ3, A0A8I3MUF0
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    104546959..104586647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005616222.4 → XP_005616279.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

    See identical proteins and their annotated locations for XP_005616279.1

    UniProtKB/TrEMBL
    A0A8C0PVK3, A0A8C0R3W1
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat

  2. XM_845900.6 → XP_850993.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2

    See identical proteins and their annotated locations for XP_850993.1

    UniProtKB/TrEMBL
    A0A8C0L2V5, A0A8C0PZQ3, A0A8I3MUF0
    Conserved Domains (3) summary
    COG1413
    Location:187 → 462
    HEAT; HEAT repeat [General function prediction only]
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:166 → 196
    HEAT; HEAT repeat
Nucleotide Protein
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