KYNU kynureninase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: KYNUprovided by VGNC
Official Full Name: kynureninaseprovided by VGNC
Primary source: VGNC:VGNC:42555
See related: Ensembl:ENSCAFG00845013520
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 19

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	19	NC_051823.1 (46479473..46607767)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	19	NC_006601.4 (45274902..45404061)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	19	NC_049240.1 (46664690..46794435)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	19	NC_049279.1 (45139690..45268624)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	19	NC_049760.1 (45269758..45399409)

Chromosome 19 - NC_051823.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables kynureninase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in NAD biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in anthranilate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tryptophan catabolic process to kynurenine	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: kynureninase

Names: kynureninase (L-kynurenine hydrolase)

XP_022261848.1

EC 3.7.1.3

XP_038282124.1

EC 3.7.1.3

XP_038282125.1

EC 3.7.1.3

XP_038310618.1

EC 3.7.1.3

XP_038358319.1

EC 3.7.1.3

XP_038358320.1

EC 3.7.1.3

XP_038421040.1

EC 3.7.1.3

XP_038421041.1

EC 3.7.1.3

XP_038485136.1

EC 3.7.1.3

XP_038485137.1

EC 3.7.1.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051823.1 Reference ROS_Cfam_1.0

Range

46479473..46607767

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038426196.1 → XP_038282124.1 kynureninase isoform X1

UniProtKB/TrEMBL

A0A8C0KV89, A0A8C0NL95, A0A8I3S055

Related

ENSCAFP00845018924.1, ENSCAFT00845024095.1

Conserved Domains (1) summary

TIGR01814
Location:54 → 483

kynureninase
XM_038426197.1 → XP_038282125.1 kynureninase isoform X2

UniProtKB/TrEMBL

A0A8C0KV89

Conserved Domains (1) summary

TIGR01814
Location:30 → 459

kynureninase

Alternate UMICH_Zoey_3.1

Genomic

NC_049279.1 Alternate UMICH_Zoey_3.1

Range

45139690..45268624

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038502391.1 → XP_038358319.1 kynureninase isoform X1

Conserved Domains (1) summary

TIGR01814
Location:54 → 483

kynureninase
XM_038502392.1 → XP_038358320.1 kynureninase isoform X2

Conserved Domains (1) summary

TIGR01814
Location:30 → 459

kynureninase

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049760.1 Alternate UNSW_CanFamBas_1.0

Range

45269758..45399409

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038629208.1 → XP_038485136.1 kynureninase isoform X1

Conserved Domains (1) summary

TIGR01814
Location:54 → 483

kynureninase
XM_038629209.1 → XP_038485137.1 kynureninase isoform X2

Conserved Domains (1) summary

TIGR01814
Location:30 → 459

kynureninase

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049240.1 Alternate UU_Cfam_GSD_1.0

Range

46664690..46794435

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038565112.1 → XP_038421040.1 kynureninase isoform X1

UniProtKB/TrEMBL

A0A8C0KV89, A0A8C0NL95, A0A8I3S055

Conserved Domains (1) summary

TIGR01814
Location:54 → 483

kynureninase
XM_038565113.1 → XP_038421041.1 kynureninase isoform X2

UniProtKB/TrEMBL

A0A8C0KV89

Conserved Domains (1) summary

TIGR01814
Location:30 → 459

kynureninase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

45274902..45404061

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_022406140.2 → XP_022261848.1 kynureninase isoform X1

UniProtKB/TrEMBL

A0A8C0KV89, A0A8C0NL95, A0A8I3S055

Conserved Domains (1) summary

TIGR01814
Location:54 → 483

kynureninase
XM_038454690.1 → XP_038310618.1 kynureninase isoform X2

UniProtKB/TrEMBL

A0A8C0KV89

Conserved Domains (1) summary

TIGR01814
Location:30 → 459

kynureninase