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BAD BCL2 associated agonist of cell death [ Canis lupus familiaris (dog) ]

Gene ID: 483763, updated on 5-Mar-2024

Summary

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Official Symbol
BADprovided by VGNC
Official Full Name
BCL2 associated agonist of cell deathprovided by VGNC
Primary source
VGNC:VGNC:38362
See related
Ensembl:ENSCAFG00845030649
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (53826736..53836956)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (51388992..51398261)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (53289648..53298901)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (52929992..52939466)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (52505744..52514998)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 4 Neighboring gene G protein-coupled receptor 137 Neighboring gene phospholipase C beta 3 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [Effect of valsartan and carnitine on cardiomyocyte Calpain-1 and Bcl-xl expressions of dogs with chronic alcohol intake-induced cardiomyopathy]. Sang Y, et al. Zhonghua Xin Xue Guan Bing Za Zhi, 2011 May. PMID 21781600

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Valsartan and carnitine could reduce alcoholic cardiomyopathy by downregulating Calpain-1 and Bad protein expression and upregulating expression of Bcl-xl protein.
    Title: [Effect of valsartan and carnitine on cardiomyocyte Calpain-1 and Bcl-xl expressions of dogs with chronic alcohol intake-induced cardiomyopathy].
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bcl2-associated agonist of cell death
Names
BCL2-antagonist of cell death

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031820.1 → NP_001026990.1  bcl2-associated agonist of cell death

    See identical proteins and their annotated locations for NP_001026990.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ127247
    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Related
    ENSCAFP00845042735.1, ENSCAFT00845054387.1
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    53826736..53836956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423458.1 → XP_038279386.1  bcl2-associated agonist of cell death isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

  2. XM_038423456.1 → XP_038279384.1  bcl2-associated agonist of cell death isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

  3. XM_038423460.1 → XP_038279388.1  bcl2-associated agonist of cell death isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

  4. XM_038423457.1 → XP_038279385.1  bcl2-associated agonist of cell death isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

  5. XM_038423459.1 → XP_038279387.1  bcl2-associated agonist of cell death isoform X1

    UniProtKB/TrEMBL
    A0A8C0KNS8, A0A8C0N2N7, F1PK10, Q45KI9
    Conserved Domains (1) summary
    pfam10514
    Location:1 → 167
    Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    52929992..52939466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    52505744..52514998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    53289648..53298901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51388992..51398261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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