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DHCR7 7-dehydrocholesterol reductase [ Canis lupus familiaris (dog) ]

Gene ID: 483675, updated on 5-Mar-2024

Summary

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Official Symbol
DHCR7provided by VGNC
Official Full Name
7-dehydrocholesterol reductaseprovided by VGNC
Primary source
VGNC:VGNC:39927
See related
Ensembl:ENSCAFG00845013203
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See DHCR7 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (47935184..47955313)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (45862457..45882527)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (47708851..47728938)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (47376200..47396229)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (46962021..46982089)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene NAD synthetase 1 Neighboring gene mas-related G-protein coupled receptor member X2 Neighboring gene actin epsilon 1 Neighboring gene SH3 and multiple ankyrin repeat domains 2 Neighboring gene uncharacterized LOC119864245

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 7-dehydrocholesterol reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brassinosteroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
7-dehydrocholesterol reductase
XP_005631422.1
XP_005631423.1
XP_038280574.1
XP_038280575.1
XP_038280576.1
XP_038280577.1
XP_038310061.1
XP_038356870.1
XP_038356871.1
XP_038356872.1
XP_038356873.1
XP_038419547.1
XP_038419548.1
XP_038419549.1
XP_038419550.1
XP_038483665.1
XP_038483666.1
XP_038483667.1
XP_038483668.1
XP_540796.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    47935184..47955313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424648.1 → XP_038280576.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8I3NZB2
    Related
    ENSCAFP00845018454.1, ENSCAFT00845023511.1
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  2. XM_038424649.1 → XP_038280577.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8I3NZB2
    Related
    ENSCAFP00845018487.1, ENSCAFT00845023549.1
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  3. XM_038424646.1 → XP_038280574.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8I3NZB2
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  4. XM_038424647.1 → XP_038280575.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8I3NZB2
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    47376200..47396229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038500944.1 → XP_038356872.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  2. XM_038500945.1 → XP_038356873.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  3. XM_038500942.1 → XP_038356870.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  4. XM_038500943.1 → XP_038356871.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    46962021..46982089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038627739.1 → XP_038483667.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  2. XM_038627740.1 → XP_038483668.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  3. XM_038627737.1 → XP_038483665.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  4. XM_038627738.1 → XP_038483666.1  7-dehydrocholesterol reductase

    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    47708851..47728938
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038563621.1 → XP_038419549.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  2. XM_038563622.1 → XP_038419550.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  3. XM_038563619.1 → XP_038419547.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  4. XM_038563620.1 → XP_038419548.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    45862457..45882527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038454133.1 → XP_038310061.1  7-dehydrocholesterol reductase

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  2. XM_540796.6 → XP_540796.2  7-dehydrocholesterol reductase

    See identical proteins and their annotated locations for XP_540796.2

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  3. XM_005631366.4 → XP_005631423.1  7-dehydrocholesterol reductase

    See identical proteins and their annotated locations for XP_005631423.1

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase

  4. XM_005631365.4 → XP_005631422.1  7-dehydrocholesterol reductase

    See identical proteins and their annotated locations for XP_005631422.1

    UniProtKB/TrEMBL
    A0A8C0KSQ7, A0A8C0PLQ7, A0A8P0NCH6
    Conserved Domains (1) summary
    cl21511
    Location:93 → 475
    PEMT; Phospholipid methyltransferase
Nucleotide Protein
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