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PTPN12 protein tyrosine phosphatase non-receptor type 12 [ Canis lupus familiaris (dog) ]

Gene ID: 483277, updated on 5-Mar-2024

Summary

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Official Symbol
PTPN12provided by VGNC
Official Full Name
protein tyrosine phosphatase non-receptor type 12provided by VGNC
Primary source
VGNC:VGNC:45169
See related
Ensembl:ENSCAFG00845022208
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (17927205..18011994)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (17266233..17315593)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (17886436..17971250)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (17677847..17762567)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (17617247..17702020)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102154601 Neighboring gene uncharacterized LOC119864103 Neighboring gene uncharacterized LOC102154647 Neighboring gene uncharacterized LOC119864181 Neighboring gene uncharacterized LOC119864182 Neighboring gene uncharacterized LOC119864183

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables non-membrane spanning protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein phosphatase non-receptor type 12
XP_038279830.1
XP_038279831.1
XP_038279832.1
XP_038279833.1
XP_038279834.1
XP_038310228.1
XP_038310229.1
XP_038356192.1
XP_038356193.1
XP_038356194.1
XP_038356195.1
XP_038356196.1
XP_038418737.1
XP_038418738.1
XP_038418739.1
XP_038418740.1
XP_038418741.1
XP_038482860.1
XP_038482861.1
XP_038482862.1
XP_038482863.1
XP_038482864.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    17927205..18011994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423902.1 → XP_038279830.1  tyrosine-protein phosphatase non-receptor type 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N9N1, A0A8C0R625, A0A8C0SYP1, A0A8I3PDX7, A0A8I3PFU2
    Related
    ENSCAFP00845030709.1, ENSCAFT00845039209.1
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  2. XM_038423905.1 → XP_038279833.1  tyrosine-protein phosphatase non-receptor type 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LA38, A0A8C0T233, A0A8C0T2J8, A0A8I3PR52
    Related
    ENSCAFP00845030978.1, ENSCAFT00845039527.1
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  3. XM_038423903.1 → XP_038279831.1  tyrosine-protein phosphatase non-receptor type 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9N1, A0A8I3PFU2
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  4. XM_038423904.1 → XP_038279832.1  tyrosine-protein phosphatase non-receptor type 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SYW1, A0A8C0Z106
    Conserved Domains (1) summary
    cl28904
    Location:13 → 277
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_038423906.1 → XP_038279834.1  tyrosine-protein phosphatase non-receptor type 12 isoform X5

    UniProtKB/TrEMBL
    A0A8C0SYW1, A0A8C0SZX0, A0A8I3PFX7
    Related
    ENSCAFP00845031215.1, ENSCAFT00845039857.1
    Conserved Domains (1) summary
    cl28904
    Location:12 → 239
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    17677847..17762567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038500264.1 → XP_038356192.1  tyrosine-protein phosphatase non-receptor type 12 isoform X1

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  2. XM_038500267.1 → XP_038356195.1  tyrosine-protein phosphatase non-receptor type 12 isoform X4

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  3. XM_038500265.1 → XP_038356193.1  tyrosine-protein phosphatase non-receptor type 12 isoform X2

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  4. XM_038500266.1 → XP_038356194.1  tyrosine-protein phosphatase non-receptor type 12 isoform X3

    Conserved Domains (1) summary
    cl28904
    Location:13 → 277
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_038500268.1 → XP_038356196.1  tyrosine-protein phosphatase non-receptor type 12 isoform X5

    Conserved Domains (1) summary
    cl28904
    Location:12 → 239
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    17617247..17702020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038626932.1 → XP_038482860.1  tyrosine-protein phosphatase non-receptor type 12 isoform X1

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  2. XM_038626935.1 → XP_038482863.1  tyrosine-protein phosphatase non-receptor type 12 isoform X4

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  3. XM_038626933.1 → XP_038482861.1  tyrosine-protein phosphatase non-receptor type 12 isoform X2

    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  4. XM_038626934.1 → XP_038482862.1  tyrosine-protein phosphatase non-receptor type 12 isoform X3

    Conserved Domains (1) summary
    cl28904
    Location:13 → 277
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_038626936.1 → XP_038482864.1  tyrosine-protein phosphatase non-receptor type 12 isoform X5

    Conserved Domains (1) summary
    cl28904
    Location:12 → 239
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    17886436..17971250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562809.1 → XP_038418737.1  tyrosine-protein phosphatase non-receptor type 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0N9N1, A0A8C0R625, A0A8C0SYP1, A0A8I3PDX7, A0A8I3PFU2
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  2. XM_038562812.1 → XP_038418740.1  tyrosine-protein phosphatase non-receptor type 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LA38, A0A8C0T233, A0A8C0T2J8, A0A8I3PR52
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  3. XM_038562810.1 → XP_038418738.1  tyrosine-protein phosphatase non-receptor type 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9N1, A0A8I3PFU2
    Conserved Domains (1) summary
    cd14604
    Location:2 → 298
    PTPc-N12; catalytic domain of tyrosine-protein phosphatase non-receptor type 12

  4. XM_038562811.1 → XP_038418739.1  tyrosine-protein phosphatase non-receptor type 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SYW1, A0A8C0Z106
    Conserved Domains (1) summary
    cl28904
    Location:13 → 277
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  5. XM_038562813.1 → XP_038418741.1  tyrosine-protein phosphatase non-receptor type 12 isoform X5

    UniProtKB/TrEMBL
    A0A8C0SYW1, A0A8C0SZX0, A0A8I3PFX7
    Conserved Domains (1) summary
    cl28904
    Location:12 → 239
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    17266233..17315593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038454300.1 → XP_038310228.1  tyrosine-protein phosphatase non-receptor type 12 isoform X6

    Conserved Domains (1) summary
    cl28904
    Location:2 → 140
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  2. XM_038454301.1 → XP_038310229.1  tyrosine-protein phosphatase non-receptor type 12 isoform X7

    Conserved Domains (1) summary
    cl28904
    Location:13 → 119
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
Nucleotide Protein
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