SFRP4 secreted frizzled related protein 4 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: SFRP4provided by VGNC
Official Full Name: secreted frizzled related protein 4provided by VGNC
Primary source: VGNC:VGNC:46082
See related: Ensembl:ENSCAFG00845022126
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	18	NC_051822.1 (12289459..12299240)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	18	NC_006600.4 (11662597..11672449)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	18	NC_049239.1 (12254578..12264365)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	18	NC_049278.1 (12106943..12116697)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	18	NC_049759.1 (12027094..12036537)

Chromosome 18 - NC_051822.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Wnt-protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in non-canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: secreted frizzled-related protein 4; secreted frizzled-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051822.1 Reference ROS_Cfam_1.0

Range

12289459..12299240

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038423732.1 → XP_038279660.1 secreted frizzled-related protein 4

UniProtKB/TrEMBL

A0A8C0LFA9, A0A8C0P4I1, A0A8C0S8S4, A0A8I3S2W9

Related

ENSCAFP00845030581.1, ENSCAFT00845039041.1

Conserved Domains (2) summary

cl02447
Location:21 → 147

CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

cl02512
Location:189 → 297

NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049278.1 Alternate UMICH_Zoey_3.1

Range

12106943..12116697

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038500089.1 → XP_038356017.1 LOW QUALITY PROTEIN: secreted frizzled-related protein 4

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049759.1 Alternate UNSW_CanFamBas_1.0

Range

12027094..12036537

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038626761.1 → XP_038482689.1 secreted frizzled-related protein 4

Conserved Domains (2) summary

cl02447
Location:21 → 147

CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

cl02512
Location:189 → 297

NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049239.1 Alternate UU_Cfam_GSD_1.0

Range

12254578..12264365

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038562679.1 → XP_038418607.1 secreted frizzled-related protein 4

UniProtKB/TrEMBL

A0A8C0LFA9, A0A8C0P4I1, A0A8C0S8S4, A0A8I3S2W9

Conserved Domains (2) summary

cl02447
Location:21 → 147

CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

cl02512
Location:189 → 297

NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

11662597..11672449

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_540377.7 → XP_540377.3 secreted frizzled-related protein 4

UniProtKB/TrEMBL

A0A8C0LFA9, A0A8C0P4I1, A0A8C0S8S4, A0A8I3S2W9

Conserved Domains (2) summary

cl02447
Location:21 → 147

CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

cl02512
Location:189 → 297

NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...