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RAP1A RAP1A, member of RAS oncogene family [ Canis lupus familiaris (dog) ]

Gene ID: 483225, updated on 5-Mar-2024

Summary

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Official Symbol
RAP1Aprovided by VGNC
Official Full Name
RAP1A, member of RAS oncogene familyprovided by VGNC
Primary source
VGNC:VGNC:49954
See related
Ensembl:ENSCAFG00845008254
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (64898732..64969490, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (63239140..63309862, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (64488459..64559217, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (63631539..63702422, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (63690887..63761587, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090741 Neighboring gene inka box actin regulator 2 Neighboring gene uncharacterized LOC111090743 Neighboring gene adenosine A3 receptor Neighboring gene transmembrane and immunoglobulin domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rap protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to cAMP IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of synaptic vesicle exocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-related protein Rap-1A
XP_022260756.1
XP_022260757.1
XP_038279239.1
XP_038279240.1
XP_038279241.1
XP_038279242.1
XP_038308939.1
XP_038308940.1
XP_038355745.1
XP_038355746.1
XP_038355747.1
XP_038355748.1
XP_038418304.1
XP_038418305.1
XP_038418306.1
XP_038418307.1
XP_038482401.1
XP_038482402.1
XP_038482403.1
XP_038482404.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    64898732..64969490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423312.1 → XP_038279240.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Related
    ENSCAFP00845011256.1, ENSCAFT00845014531.1
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_038423311.1 → XP_038279239.1  ras-related protein Rap-1A isoform X1

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:27 → 177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038423314.1 → XP_038279242.1  ras-related protein Rap-1A isoform X3

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:13 → 163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_038423313.1 → XP_038279241.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    63631539..63702422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499818.1 → XP_038355746.1  ras-related protein Rap-1A isoform X2

    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_038499817.1 → XP_038355745.1  ras-related protein Rap-1A isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:27 → 177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038499820.1 → XP_038355748.1  ras-related protein Rap-1A isoform X3

    Conserved Domains (1) summary
    cl38936
    Location:13 → 163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_038499819.1 → XP_038355747.1  ras-related protein Rap-1A isoform X2

    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    63690887..63761587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038626474.1 → XP_038482402.1  ras-related protein Rap-1A isoform X2

    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_038626473.1 → XP_038482401.1  ras-related protein Rap-1A isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:27 → 177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038626476.1 → XP_038482404.1  ras-related protein Rap-1A isoform X3

    Conserved Domains (1) summary
    cl38936
    Location:13 → 163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_038626475.1 → XP_038482403.1  ras-related protein Rap-1A isoform X2

    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    64488459..64559217 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562377.1 → XP_038418305.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_038562376.1 → XP_038418304.1  ras-related protein Rap-1A isoform X1

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:27 → 177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038562379.1 → XP_038418307.1  ras-related protein Rap-1A isoform X3

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:13 → 163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_038562378.1 → XP_038418306.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    63239140..63309862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453011.1 → XP_038308939.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_022405048.2 → XP_022260756.1  ras-related protein Rap-1A isoform X1

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:27 → 177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_022405049.2 → XP_022260757.1  ras-related protein Rap-1A isoform X3

    UniProtKB/TrEMBL
    A0A8I3NJT0, A0A8P0SUT4
    Conserved Domains (1) summary
    cl38936
    Location:13 → 163
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_038453012.1 → XP_038308940.1  ras-related protein Rap-1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0K589, A0A8C0YYH2, A0A8I3NJT0, A0A8I3RUF3, A0A8P0SUT4
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms
Nucleotide Protein
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