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ASCL1 achaete-scute family bHLH transcription factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 482628, updated on 5-Mar-2024

Summary

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Official Symbol
ASCL1provided by VGNC
Official Full Name
achaete-scute family bHLH transcription factor 1provided by VGNC
Primary source
VGNC:VGNC:38173
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ASH1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
2
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (42349900..42352808)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (42062179..42065075)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (41986771..41989679)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (41619328..41622224)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (41717251..41720147)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene phenylalanine hydroxylase Neighboring gene uncharacterized LOC119869373 Neighboring gene uncharacterized LOC102152557 Neighboring gene uncharacterized LOC111090068

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Wang XH, et al. Mol Genet Genomics, 2015 Apr. PMID 25403511

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sensory organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
achaete-scute homolog 1
Names
achaete-scute complex homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    42349900..42352808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688456.1 → XP_038544384.1  achaete-scute homolog 1

    UniProtKB/TrEMBL
    A0A8C0SZM8, A0A8I3N3A3
    Conserved Domains (1) summary
    cd19742
    Location:123 → 193
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

  2. XM_038688457.1 → XP_038544385.1  achaete-scute homolog 1

    UniProtKB/TrEMBL
    A0A8C0SZM8, A0A8I3N3A3
    Conserved Domains (1) summary
    cd19742
    Location:123 → 193
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    41619328..41622224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496466.1 → XP_038352394.1  achaete-scute homolog 1

    Conserved Domains (1) summary
    cd19742
    Location:119 → 189
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

  2. XM_038496467.1 → XP_038352395.1  achaete-scute homolog 1

    Conserved Domains (1) summary
    cd19742
    Location:119 → 189
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    41717251..41720147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622785.1 → XP_038478713.1  achaete-scute homolog 1

    Conserved Domains (1) summary
    cd19742
    Location:119 → 189
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

  2. XM_038622786.1 → XP_038478714.1  achaete-scute homolog 1

    Conserved Domains (1) summary
    cd19742
    Location:119 → 189
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    41986771..41989679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558863.1 → XP_038414791.1  achaete-scute homolog 1

    UniProtKB/TrEMBL
    A0A8C0SZM8, A0A8I3N3A3
    Conserved Domains (1) summary
    cd19742
    Location:123 → 193
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

  2. XM_038558864.1 → XP_038414792.1  achaete-scute homolog 1

    UniProtKB/TrEMBL
    A0A8C0SZM8, A0A8I3N3A3
    Conserved Domains (1) summary
    cd19742
    Location:123 → 193
    bHLH_TS_ASCL1_Mash1; basic helix-loop-helix (bHLH) domain found in achaete-scute-like protein 1 (ASCL-1) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    42062179..42065075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005629297.4 → XP_005629354.1  achaete-scute homolog 1

    See identical proteins and their annotated locations for XP_005629354.1

    UniProtKB/TrEMBL
    A0A8C0LGQ4, A0A8C0SZM8, A0A8I3N3A3, A0A8P0SCJ5
    Conserved Domains (1) summary
    smart00353
    Location:138 → 180
    HLH; helix loop helix domain

  2. XM_539745.7 → XP_539745.3  achaete-scute homolog 1

    See identical proteins and their annotated locations for XP_539745.3

    UniProtKB/TrEMBL
    A0A8C0LGQ4, A0A8C0SZM8, A0A8I3N3A3, A0A8P0SCJ5
    Conserved Domains (1) summary
    smart00353
    Location:138 → 180
    HLH; helix loop helix domain
Nucleotide Protein
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