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MKNK1 MAPK interacting serine/threonine kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 482509, updated on 5-Mar-2024

Summary

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Official Symbol
MKNK1provided by VGNC
Official Full Name
MAPK interacting serine/threonine kinase 1provided by VGNC
Primary source
VGNC:VGNC:54216
See related
Ensembl:ENSCAFG00845018913
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MKNK1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (14008202..14049444)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (13978161..14019402)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (13947345..13988638)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (13809430..13850723)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (13878036..13919318)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 1 Neighboring gene MOB kinase activator 3C Neighboring gene uncharacterized LOC106559794 Neighboring gene kinocilin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MAP kinase-interacting serine/threonine-protein kinase 1
Names
MAP kinase interacting serine/threonine kinase 1
XP_013975135.1
XP_038307408.1
XP_038307414.1
XP_038307422.1
XP_038307425.1
XP_038307428.1
XP_038351703.1
XP_038351704.1
XP_038351705.1
XP_038351706.1
XP_038351707.1
XP_038351708.1
XP_038414077.1
XP_038414078.1
XP_038414079.1
XP_038414080.1
XP_038414081.1
XP_038414082.1
XP_038477948.1
XP_038477949.1
XP_038477951.1
XP_038477952.1
XP_038477953.1
XP_038477954.1
XP_038543699.1
XP_038543700.1
XP_038543701.1
XP_038543702.1
XP_038543703.1
XP_038543704.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    14008202..14049444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687772.1 → XP_038543700.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  2. XM_038687771.1 → XP_038543699.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  3. XM_038687775.1 → XP_038543703.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0NXI9, A0A8I3PD30
    Related
    ENSCAFP00845026189.1, ENSCAFT00845033456.1
    Conserved Domains (1) summary
    cd14174
    Location:40 → 328
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  4. XM_038687776.1 → XP_038543704.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0YZG2, A0A8I3PFZ5
    Related
    ENSCAFP00845026442.1, ENSCAFT00845033786.1
    Conserved Domains (1) summary
    cd14174
    Location:34 → 322
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  5. XM_038687773.1 → XP_038543701.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  6. XM_038687774.1 → XP_038543702.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    13809430..13850723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038495776.1 → XP_038351704.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  2. XM_038495775.1 → XP_038351703.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  3. XM_038495779.1 → XP_038351707.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2

    Conserved Domains (1) summary
    cd14174
    Location:40 → 328
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  4. XM_038495780.1 → XP_038351708.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3

    Conserved Domains (1) summary
    cd14174
    Location:34 → 322
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  5. XM_038495777.1 → XP_038351705.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  6. XM_038495778.1 → XP_038351706.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    13878036..13919318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622021.1 → XP_038477949.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  2. XM_038622020.1 → XP_038477948.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  3. XM_038622025.1 → XP_038477953.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2

    Conserved Domains (1) summary
    cd14174
    Location:40 → 328
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  4. XM_038622026.1 → XP_038477954.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3

    Conserved Domains (1) summary
    cd14174
    Location:34 → 322
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  5. XM_038622023.1 → XP_038477951.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  6. XM_038622024.1 → XP_038477952.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    13947345..13988638
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558150.1 → XP_038414078.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  2. XM_038558149.1 → XP_038414077.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  3. XM_038558153.1 → XP_038414081.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0NXI9, A0A8I3PD30
    Conserved Domains (1) summary
    cd14174
    Location:40 → 328
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  4. XM_038558154.1 → XP_038414082.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0YZG2, A0A8I3PFZ5
    Conserved Domains (1) summary
    cd14174
    Location:34 → 322
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  5. XM_038558151.1 → XP_038414079.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  6. XM_038558152.1 → XP_038414080.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13978161..14019402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038451486.1 → XP_038307414.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  2. XM_038451480.1 → XP_038307408.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  3. XM_014119660.3 → XP_013975135.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0NXI9, A0A8I3PD30
    Conserved Domains (1) summary
    cd14174
    Location:40 → 328
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  4. XM_038451500.1 → XP_038307428.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KP64, A0A8C0YZG2, A0A8I3PFZ5
    Conserved Domains (1) summary
    cd14174
    Location:34 → 322
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  5. XM_038451494.1 → XP_038307422.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1

  6. XM_038451497.1 → XP_038307425.1  MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KP64
    Conserved Domains (1) summary
    cd14174
    Location:69 → 357
    STKc_Mnk1; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase signal-integrating kinase 1
Nucleotide Protein
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