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ABCB4 ATP binding cassette subfamily B member 4 [ Canis lupus familiaris (dog) ]

Gene ID: 482284, updated on 17-Aug-2024

Summary

Official Symbol
ABCB4provided by VGNC
Official Full Name
ATP binding cassette subfamily B member 4provided by VGNC
Primary source
VGNC:VGNC:37434
See related
Ensembl:ENSCAFG00845007730
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See ABCB4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
28
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (13307604..13379530, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (13114115..13185936, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (13520259..13592210, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (13510779..13582706, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (13236739..13308588, complement)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098739 Neighboring gene carnitine O-octanoyltransferase Neighboring gene ATP binding cassette subfamily B member 1 Neighboring gene RUN domain containing 3B Neighboring gene small ubiquitin-related modifier 2-like

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity PubMed 
enables ATP binding PubMed 
enables ATP hydrolysis activity PubMed 
Component Evidence Code Pubs
located_in membrane PubMed 

General protein information

Preferred Names
phosphatidylcholine translocator ABCB4
XP_013974663.2
XP_022282996.2
XP_038299678.1
XP_038299689.1
XP_038299690.1
XP_038299693.1
XP_038350316.1
XP_038350317.1
XP_038350318.1
XP_038350319.1
XP_038350320.1
XP_038350321.1
XP_038350322.1
XP_038412611.1
XP_038412612.1
XP_038412613.1
XP_038412614.1
XP_038412615.1
XP_038412616.1
XP_038412617.1
XP_038476546.1
XP_038476547.1
XP_038476548.1
XP_038476549.1
XP_038476550.1
XP_038476551.1
XP_038476552.1
XP_038542235.1
XP_038542236.1
XP_038542237.1
XP_038542238.1
XP_038542239.1
XP_038542240.1
XP_038542241.1
XP_539403.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    13307604..13379530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686311.1XP_038542239.1  phosphatidylcholine translocator ABCB4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:141228
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  2. XM_038686310.1XP_038542238.1  phosphatidylcholine translocator ABCB4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R5C0
    Conserved Domains (1) summary
    PTZ00265
    Location:191235
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  3. XM_038686308.1XP_038542236.1  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Related
    ENSCAFP00845010591.1, ENSCAFT00845013639.1
    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  4. XM_038686309.1XP_038542237.1  phosphatidylcholine translocator ABCB4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Conserved Domains (1) summary
    PTZ00265
    Location:471261
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  5. XM_038686307.1XP_038542235.1  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  6. XM_038686312.1XP_038542240.1  phosphatidylcholine translocator ABCB4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:31075
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  7. XM_038686313.1XP_038542241.1  phosphatidylcholine translocator ABCB4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:371048
    PTZ00265; multidrug resistance protein (mdr1); Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    13510779..13582706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494392.1XP_038350320.1  phosphatidylcholine translocator ABCB4 isoform X4

    Conserved Domains (1) summary
    PTZ00265
    Location:141228
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  2. XM_038494391.1XP_038350319.1  phosphatidylcholine translocator ABCB4 isoform X3

    Conserved Domains (1) summary
    PTZ00265
    Location:191235
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  3. XM_038494389.1XP_038350317.1  phosphatidylcholine translocator ABCB4 isoform X1

    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  4. XM_038494390.1XP_038350318.1  phosphatidylcholine translocator ABCB4 isoform X2

    Conserved Domains (1) summary
    PTZ00265
    Location:471261
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  5. XM_038494388.1XP_038350316.1  phosphatidylcholine translocator ABCB4 isoform X1

    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  6. XM_038494393.1XP_038350321.1  phosphatidylcholine translocator ABCB4 isoform X5

    Conserved Domains (1) summary
    PTZ00265
    Location:31075
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  7. XM_038494394.1XP_038350322.1  phosphatidylcholine translocator ABCB4 isoform X6

    Conserved Domains (1) summary
    PTZ00265
    Location:371048
    PTZ00265; multidrug resistance protein (mdr1); Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    13236739..13308588 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620622.1XP_038476550.1  phosphatidylcholine translocator ABCB4 isoform X4

  2. XM_038620621.1XP_038476549.1  phosphatidylcholine translocator ABCB4 isoform X3

  3. XM_038620619.1XP_038476547.1  phosphatidylcholine translocator ABCB4 isoform X1

  4. XM_038620620.1XP_038476548.1  phosphatidylcholine translocator ABCB4 isoform X2

  5. XM_038620618.1XP_038476546.1  phosphatidylcholine translocator ABCB4 isoform X1

  6. XM_038620623.1XP_038476551.1  phosphatidylcholine translocator ABCB4 isoform X5

  7. XM_038620624.1XP_038476552.1  phosphatidylcholine translocator ABCB4 isoform X6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    13520259..13592210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556687.1XP_038412615.1  phosphatidylcholine translocator ABCB4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SGW1
  2. XM_038556686.1XP_038412614.1  phosphatidylcholine translocator ABCB4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R5C0
  3. XM_038556684.1XP_038412612.1  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MH38, A0A8I3N6T3
  4. XM_038556685.1XP_038412613.1  phosphatidylcholine translocator ABCB4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MH38, A0A8I3N6T3
  5. XM_038556683.1XP_038412611.1  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MH38, A0A8I3N6T3
  6. XM_038556688.1XP_038412616.1  phosphatidylcholine translocator ABCB4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0SGW1
  7. XM_038556689.1XP_038412617.1  phosphatidylcholine translocator ABCB4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0SGW1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13114115..13185936 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038443762.1XP_038299690.1  phosphatidylcholine translocator ABCB4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:141228
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  2. XM_038443761.1XP_038299689.1  phosphatidylcholine translocator ABCB4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R5C0
    Conserved Domains (1) summary
    PTZ00265
    Location:191235
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  3. XM_539403.7XP_539403.4  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  4. XM_014119188.3XP_013974663.2  phosphatidylcholine translocator ABCB4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Conserved Domains (1) summary
    PTZ00265
    Location:471261
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  5. XM_038443750.1XP_038299678.1  phosphatidylcholine translocator ABCB4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3N6T3
    Conserved Domains (1) summary
    PTZ00265
    Location:261268
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  6. XM_022427288.2XP_022282996.2  phosphatidylcholine translocator ABCB4 isoform X5

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:31075
    PTZ00265; multidrug resistance protein (mdr1); Provisional
  7. XM_038443765.1XP_038299693.1  phosphatidylcholine translocator ABCB4 isoform X6

    UniProtKB/TrEMBL
    A0A8C0SGW1
    Conserved Domains (1) summary
    PTZ00265
    Location:371048
    PTZ00265; multidrug resistance protein (mdr1); Provisional
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