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RXRB retinoid X receptor beta [ Canis lupus familiaris (dog) ]

Gene ID: 481735, updated on 5-Mar-2024

Summary

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Official Symbol
RXRBprovided by VGNC
Official Full Name
retinoid X receptor betaprovided by VGNC
Primary source
VGNC:VGNC:45818
See related
Ensembl:ENSCAFG00845020447
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
NR2B2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (2987789..2994513, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (2738197..2744918, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (2811921..2818640, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (2655982..2662701, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (2737356..2744070, complement)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene HLA class II histocompatibility antigen, DP beta 1 chain-like Neighboring gene uncharacterized LOC102152980 Neighboring gene 60S ribosomal protein L11-like Neighboring gene collagen type XI alpha 2 chain Neighboring gene solute carrier family 39 member 7 Neighboring gene hydroxysteroid 17-beta dehydrogenase 8 Neighboring gene microRNA mir-219-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors. Waxman JS, et al. Dev Dyn, 2007 Feb. PMID 17195188

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables retinoic acid-responsive element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to retinoic acid IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinoic acid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinoic acid receptor RXR-beta; LOW QUALITY PROTEIN: retinoic acid receptor RXR-beta
Names
Nuclear receptor subfamily 2 group B member 2
Retinoic acid receptor RXR-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    2987789..2994513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038683176.1 → XP_038539104.1  retinoic acid receptor RXR-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JNP4, A0A8C0NBV8, A0A8I3PCA9, Q5TJF8
    Related
    ENSCAFP00845028203.1, ENSCAFT00845036036.1
    Conserved Domains (3) summary
    cd06943
    Location:298 → 515
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:204 → 279
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:129 → 189
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  2. XM_038683177.1 → XP_038539105.1  retinoic acid receptor RXR-beta isoform X2

    UniProtKB/Swiss-Prot
    Q5TJF7
    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (3) summary
    cd06943
    Location:298 → 511
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:204 → 279
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:129 → 189
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  3. XM_038683178.1 → XP_038539106.1  retinoic acid receptor RXR-beta isoform X3

    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (2) summary
    cd06943
    Location:202 → 419
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:108 → 183
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    2655982..2662701 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038491481.1 → XP_038347409.1  retinoic acid receptor RXR-beta isoform X1

    Conserved Domains (3) summary
    cd06943
    Location:297 → 514
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  2. XM_038491482.1 → XP_038347410.1  retinoic acid receptor RXR-beta isoform X2

    Conserved Domains (3) summary
    cd06943
    Location:297 → 510
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  3. XM_038491484.1 → XP_038347412.1  retinoic acid receptor RXR-beta isoform X3

    Conserved Domains (2) summary
    cd06943
    Location:201 → 418
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:107 → 182
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    2737356..2744070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038617570.1 → XP_038473498.1  LOW QUALITY PROTEIN: retinoic acid receptor RXR-beta isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    2811921..2818640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553705.1 → XP_038409633.1  retinoic acid receptor RXR-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0T8B7, A0A8P0N438, Q5TJF8
    Conserved Domains (3) summary
    cd06943
    Location:297 → 514
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  2. XM_038553706.1 → XP_038409634.1  retinoic acid receptor RXR-beta isoform X2

    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (3) summary
    cd06943
    Location:297 → 510
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  3. XM_038553707.1 → XP_038409635.1  retinoic acid receptor RXR-beta isoform X3

    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (2) summary
    cd06943
    Location:201 → 418
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:107 → 182
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2738197..2744918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627197.3 → XP_005627254.1  retinoic acid receptor RXR-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0T8B7, A0A8P0N438, Q5TJF8
    Conserved Domains (3) summary
    cd06943
    Location:297 → 514
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  2. XM_538856.7 → XP_538856.2  retinoic acid receptor RXR-beta isoform X2

    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (3) summary
    cd06943
    Location:297 → 510
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:203 → 278
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:128 → 188
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

  3. XM_014118362.3 → XP_013973837.1  retinoic acid receptor RXR-beta isoform X3

    UniProtKB/TrEMBL
    Q5TJF8
    Conserved Domains (2) summary
    cd06943
    Location:201 → 418
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:107 → 182
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5TJF7.1 GenPept UniProtKB/Swiss-Prot:Q5TJF7

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