SPRED2 sprouty related EVH1 domain containing 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: SPRED2provided by VGNC
Official Full Name: sprouty related EVH1 domain containing 2provided by VGNC
Primary source: VGNC:VGNC:46763
See related: Ensembl:ENSCAFG00845022023
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	10	NC_051814.1 (65771737..65886366, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	10	NC_006592.4 (64648640..64763412, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	10	NC_049231.1 (66053709..66168347, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	10	NC_049270.1 (65450264..65564843, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	10	NC_049751.1 (65758109..65872866, complement)

Chromosome 10 - NC_051814.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-64931 (e-PCR)
- UniSTS:27713

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: sprouty-related, EVH1 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051814.1 Reference ROS_Cfam_1.0

Range

65771737..65886366 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038680782.1 → XP_038536710.1 sprouty-related, EVH1 domain-containing protein 2 isoform X1

UniProtKB/TrEMBL

A0A8C0R8R4, A0A8C0RLF1, A0A8I3S5D3

Related

ENSCAFP00845030472.1, ENSCAFT00845038909.1

Conserved Domains (2) summary

cd10574
Location:12 → 124

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:305 → 410

Sprouty; Sprouty protein (Spry)
XM_038680784.1 → XP_038536712.1 sprouty-related, EVH1 domain-containing protein 2 isoform X3

Conserved Domains (2) summary

cd10574
Location:1 → 104

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:285 → 390

Sprouty; Sprouty protein (Spry)
XM_038680783.1 → XP_038536711.1 sprouty-related, EVH1 domain-containing protein 2 isoform X2

UniProtKB/TrEMBL

A0A8C0NMV1, A0A8I3P9R1

Related

ENSCAFP00845030420.1, ENSCAFT00845038841.1

Conserved Domains (2) summary

cd10574
Location:9 → 121

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:302 → 407

Sprouty; Sprouty protein (Spry)

Alternate UMICH_Zoey_3.1

Genomic

NC_049270.1 Alternate UMICH_Zoey_3.1

Range

65450264..65564843 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038489469.1 → XP_038345397.1 sprouty-related, EVH1 domain-containing protein 2 isoform X1

Conserved Domains (2) summary

cd10574
Location:12 → 124

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:305 → 410

Sprouty; Sprouty protein (Spry)
XM_038489471.1 → XP_038345399.1 sprouty-related, EVH1 domain-containing protein 2 isoform X3

Conserved Domains (2) summary

cd10574
Location:1 → 104

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:285 → 390

Sprouty; Sprouty protein (Spry)
XM_038489470.1 → XP_038345398.1 sprouty-related, EVH1 domain-containing protein 2 isoform X2

Conserved Domains (2) summary

cd10574
Location:9 → 121

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:302 → 407

Sprouty; Sprouty protein (Spry)

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049751.1 Alternate UNSW_CanFamBas_1.0

Range

65758109..65872866 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038615391.1 → XP_038471319.1 sprouty-related, EVH1 domain-containing protein 2 isoform X1
XM_038615393.1 → XP_038471321.1 sprouty-related, EVH1 domain-containing protein 2 isoform X3
XM_038615392.1 → XP_038471320.1 sprouty-related, EVH1 domain-containing protein 2 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049231.1 Alternate UU_Cfam_GSD_1.0

Range

66053709..66168347 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038551454.1 → XP_038407382.1 sprouty-related, EVH1 domain-containing protein 2 isoform X1

UniProtKB/TrEMBL

A0A8C0R8R4, A0A8C0RLF1, A0A8I3S5D3

Conserved Domains (2) summary

cd10574
Location:12 → 124

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:305 → 410

Sprouty; Sprouty protein (Spry)
XM_038551456.1 → XP_038407384.1 sprouty-related, EVH1 domain-containing protein 2 isoform X3

Conserved Domains (2) summary

cd10574
Location:1 → 104

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:285 → 390

Sprouty; Sprouty protein (Spry)
XM_038551455.1 → XP_038407383.1 sprouty-related, EVH1 domain-containing protein 2 isoform X2

UniProtKB/TrEMBL

A0A8C0NMV1, A0A8I3P9R1

Conserved Domains (2) summary

cd10574
Location:9 → 121

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:302 → 407

Sprouty; Sprouty protein (Spry)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

64648640..64763412 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038649704.1 → XP_038505632.1 sprouty-related, EVH1 domain-containing protein 2 isoform X1

UniProtKB/TrEMBL

A0A8C0R8R4, A0A8C0RLF1, A0A8I3S5D3

Conserved Domains (2) summary

cd10574
Location:12 → 124

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:305 → 410

Sprouty; Sprouty protein (Spry)
XM_038649723.1 → XP_038505651.1 sprouty-related, EVH1 domain-containing protein 2 isoform X3

Conserved Domains (2) summary

cd10574
Location:1 → 104

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:285 → 390

Sprouty; Sprouty protein (Spry)
XM_538517.7 → XP_538517.2 sprouty-related, EVH1 domain-containing protein 2 isoform X2

UniProtKB/TrEMBL

A0A8C0NMV1, A0A8I3P9R1

Conserved Domains (2) summary

cd10574
Location:9 → 121

EVH1_SPRED-like; Sprouty-related EVH1 domain-containing-like proteins EVH1 domain

pfam05210
Location:302 → 407

Sprouty; Sprouty protein (Spry)