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CYP27B1 cytochrome P450 family 27 subfamily B member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 481133, updated on 5-Mar-2024

Summary

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Official Symbol
CYP27B1provided by VGNC
Official Full Name
cytochrome P450 family 27 subfamily B member 1provided by VGNC
Primary source
VGNC:VGNC:50343
See related
Ensembl:ENSCAFG00845013886
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (1834457..1840136, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (1888246..1893920, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (2179134..2184808, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (1812161..1817832, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (2054207..2059882, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 4 Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene methyltransferase 1, tRNA methylguanosine Neighboring gene EEF1A lysine methyltransferase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in C21-steroid hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to peptide hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortisol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucocorticoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; LOW QUALITY PROTEIN: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Names
cytochrome P450, family 27, subfamily B, polypeptide 1
XP_038343861.1
XP_038405754.1
XP_038469721.1
XP_038535076.1
XP_538254.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    1834457..1840136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679148.1 → XP_038535076.1  LOW QUALITY PROTEIN: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0RDD4, A0A8C0SY88, A0A8I3NU23, A0A8P0N3M3
    Related
    ENSCAFP00845019544.1, ENSCAFT00845024846.1
    Conserved Domains (1) summary
    cl41757
    Location:68 → 503
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    1812161..1817832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038487933.1 → XP_038343861.1  LOW QUALITY PROTEIN: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    2054207..2059882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038613793.1 → XP_038469721.1  25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    2179134..2184808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038549826.1 → XP_038405754.1  25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0RDD4, A0A8C0SY88, A0A8I3NU23, A0A8P0N3M3
    Conserved Domains (1) summary
    cl41757
    Location:68 → 503
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1888246..1893920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_538254.7 → XP_538254.4  25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0RDD4, A0A8C0SY88, A0A8I3NU23, A0A8P0N3M3
    Conserved Domains (1) summary
    cl41757
    Location:68 → 503
    cytochrome_P450; cytochrome P450 (CYP) superfamily
Nucleotide Protein
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