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HDAC8 histone deacetylase 8 [ Canis lupus familiaris (dog) ]

Gene ID: 480957, updated on 5-Mar-2024

Summary

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Official Symbol
HDAC8provided by VGNC
Official Full Name
histone deacetylase 8provided by VGNC
Primary source
VGNC:VGNC:50631
See related
Ensembl:ENSCAFG00845020238
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (57411265..57628877, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (47183095..47400619, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (56571889..56789465, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (55325722..55544604, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (56723145..56940470, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S4 X-linked Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 Neighboring gene uncharacterized LOC111094674 Neighboring gene U6 spliceosomal RNA Neighboring gene phosphorylase kinase regulatory subunit alpha 1 Neighboring gene doublesex- and mab-3-related transcription factor C2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone deacetylase 8
XP_005641546.1
XP_005641547.1
XP_005641549.1
XP_005641550.1
XP_038306222.1
XP_038306223.1
XP_038306224.1
XP_038306225.1
XP_038306226.1
XP_038306227.1
XP_038320433.1
XP_038379675.1
XP_038379676.1
XP_038379677.1
XP_038379678.1
XP_038379679.1
XP_038379680.1
XP_038443642.1
XP_038443643.1
XP_038443644.1
XP_038443645.1
XP_038443646.1
XP_038443647.1
XP_038508165.1
XP_038508166.1
XP_038508167.1
XP_038508168.1
XP_038508169.1
XP_038508170.1
XP_859069.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    57411265..57628877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450298.1 → XP_038306226.1  histone deacetylase 8 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_038450295.1 → XP_038306223.1  histone deacetylase 8 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PJC3
    Conserved Domains (1) summary
    cd10000
    Location:54 → 451
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_038450297.1 → XP_038306225.1  histone deacetylase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LAA4, A0A8I3PJC3, A0A8P0SUT8
    Related
    ENSCAFP00845027987.1, ENSCAFT00845035772.1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_038450299.1 → XP_038306227.1  histone deacetylase 8 isoform X6

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_038450294.1 → XP_038306222.1  histone deacetylase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_038450296.1 → XP_038306224.1  histone deacetylase 8 isoform X3

    UniProtKB/TrEMBL
    A0A8I3P9X1, A0A8I3PEJ1
    Related
    ENSCAFP00845028672.1, ENSCAFT00845036635.1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    55325722..55544604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038523751.1 → XP_038379679.1  histone deacetylase 8 isoform X5

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_038523748.1 → XP_038379676.1  histone deacetylase 8 isoform X2

    Conserved Domains (1) summary
    cd10000
    Location:54 → 451
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_038523750.1 → XP_038379678.1  histone deacetylase 8 isoform X4

    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_038523752.1 → XP_038379680.1  histone deacetylase 8 isoform X6

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_038523747.1 → XP_038379675.1  histone deacetylase 8 isoform X1

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_038523749.1 → XP_038379677.1  histone deacetylase 8 isoform X3

    Conserved Domains (1) summary
    cd10000
    Location:54 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)

RNA

  1. XR_005352212.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    56723145..56940470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652241.1 → XP_038508169.1  histone deacetylase 8 isoform X5

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_038652238.1 → XP_038508166.1  histone deacetylase 8 isoform X2

    Conserved Domains (1) summary
    cd10000
    Location:54 → 451
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_038652240.1 → XP_038508168.1  histone deacetylase 8 isoform X4

    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_038652242.1 → XP_038508170.1  histone deacetylase 8 isoform X6

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_038652237.1 → XP_038508165.1  histone deacetylase 8 isoform X1

    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_038652239.1 → XP_038508167.1  histone deacetylase 8 isoform X3

    Conserved Domains (1) summary
    cd10000
    Location:54 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    56571889..56789465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587718.1 → XP_038443646.1  histone deacetylase 8 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_038587715.1 → XP_038443643.1  histone deacetylase 8 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PJC3
    Conserved Domains (1) summary
    cd10000
    Location:54 → 451
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_038587717.1 → XP_038443645.1  histone deacetylase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LAA4, A0A8I3PJC3, A0A8P0SUT8
    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_038587719.1 → XP_038443647.1  histone deacetylase 8 isoform X6

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_038587714.1 → XP_038443642.1  histone deacetylase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_038587716.1 → XP_038443644.1  histone deacetylase 8 isoform X3

    UniProtKB/TrEMBL
    A0A8I3P9X1, A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    47183095..47400619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038464505.1 → XP_038320433.1  histone deacetylase 8 isoform X5

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_005641490.4 → XP_005641547.1  histone deacetylase 8 isoform X2

    UniProtKB/TrEMBL
    A0A8I3PJC3
    Conserved Domains (1) summary
    cd10000
    Location:54 → 451
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_005641492.4 → XP_005641549.1  histone deacetylase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LAA4, A0A8I3PJC3, A0A8P0SUT8
    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_005641493.4 → XP_005641550.1  histone deacetylase 8 isoform X6

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_005641489.4 → XP_005641546.1  histone deacetylase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_853976.6 → XP_859069.3  histone deacetylase 8 isoform X3

    UniProtKB/TrEMBL
    A0A8I3P9X1, A0A8I3PEJ1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)
Nucleotide Protein
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