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ITGAE integrin subunit alpha E [ Canis lupus familiaris (dog) ]

Gene ID: 480659, updated on 5-Mar-2024

Summary

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Official Symbol
ITGAEprovided by VGNC
Official Full Name
integrin subunit alpha Eprovided by VGNC
Primary source
VGNC:VGNC:42131
See related
Ensembl:ENSCAFG00845016713
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
32
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (48377007..48441856, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (46693946..46758709, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (47499773..47564748, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (47154687..47219366, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (47443915..47508339, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene ER membrane protein complex subunit 6 Neighboring gene purinergic receptor P2X 5 Neighboring gene U4 spliceosomal RNA Neighboring gene histone H3 associated protein kinase Neighboring gene nuclear cap binding subunit 3 Neighboring gene U6 spliceosomal RNA Neighboring gene calcium/calmodulin dependent protein kinase kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-E

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    48377007..48441856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677781.1 → XP_038533709.1  integrin alpha-E isoform X1

    UniProtKB/TrEMBL
    A0A8C0QKT2
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha

  2. XM_038677783.1 → XP_038533711.1  integrin alpha-E isoform X3

    UniProtKB/TrEMBL
    A0A8C0QKT2
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha

  3. XM_038677782.1 → XP_038533710.1  integrin alpha-E isoform X2

    UniProtKB/TrEMBL
    A0A8C0QKT2, A0A8I3RZG7
    Related
    ENSCAFP00845023297.1, ENSCAFT00845029663.1
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    47154687..47219366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486697.1 → XP_038342625.1  integrin alpha-E isoform X1

  2. XM_038486699.1 → XP_038342627.1  integrin alpha-E isoform X3

  3. XM_038486698.1 → XP_038342626.1  integrin alpha-E isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    47443915..47508339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038612505.1 → XP_038468433.1  integrin alpha-E isoform X1

  2. XM_038612507.1 → XP_038468435.1  integrin alpha-E isoform X3

  3. XM_038612506.1 → XP_038468434.1  integrin alpha-E isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    47499773..47564748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038548564.1 → XP_038404492.1  integrin alpha-E isoform X1

    UniProtKB/TrEMBL
    A0A8C0MR40

  2. XM_038548566.1 → XP_038404494.1  integrin alpha-E isoform X3

    UniProtKB/TrEMBL
    A0A8C0MR40

  3. XM_038548565.1 → XP_038404493.1  integrin alpha-E isoform X2

    UniProtKB/TrEMBL
    A0A8C0MR40

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    46693946..46758709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022423485.2 → XP_022279193.1  integrin alpha-E isoform X1

    UniProtKB/TrEMBL
    A0A8C0QKT2
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha

  2. XM_022423488.2 → XP_022279196.1  integrin alpha-E isoform X3

    UniProtKB/TrEMBL
    A0A8C0QKT2
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha

  3. XM_014116854.3 → XP_013972329.2  integrin alpha-E isoform X2

    UniProtKB/TrEMBL
    A0A8C0QKT2, A0A8P0SNR8
    Conserved Domains (3) summary
    smart00191
    Location:565 → 624
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:195 → 372
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:667 → 923
    Integrin_alpha2; Integrin alpha
Nucleotide Protein
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