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MAP2K6 mitogen-activated protein kinase kinase 6 [ Canis lupus familiaris (dog) ]

Gene ID: 480454, updated on 5-Mar-2024

Summary

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Official Symbol
MAP2K6provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 6provided by VGNC
Primary source
VGNC:VGNC:42964
See related
Ensembl:ENSCAFG00845005385
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (17501891..17623440)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (16731937..16853765)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (10965262..11086973, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (16445924..16567352)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (10966413..11088091, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 5 Neighboring gene uncharacterized LOC100684380 Neighboring gene uncharacterized LOC111097334 Neighboring gene uncharacterized LOC106559254 Neighboring gene uncharacterized LOC119873419 Neighboring gene uncharacterized LOC111097335

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of Src signal transduction pathways in scatter factor-mediated cellular protection. Fan S, et al. J Biol Chem, 2009 Mar 20. PMID 19047046, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 6; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6
XP_005624348.3
XP_005624349.1
XP_022278578.1
XP_038341186.1
XP_038402670.1
XP_038402671.1
XP_038402672.1
XP_038402674.1
XP_038466662.1
XP_038466663.1
XP_038466665.1
XP_038466666.1
XP_038532058.1
XP_038532059.1
XP_038532060.1
XP_038532061.1
XP_851023.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    17501891..17623440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676130.1 → XP_038532058.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Related
    ENSCAFP00845007481.1, ENSCAFT00845009565.1
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  2. XM_038676131.1 → XP_038532059.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  3. XM_038676132.1 → XP_038532060.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  4. XM_038676133.1 → XP_038532061.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    16445924..16567352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485258.1 → XP_038341186.1  LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    10966413..11088091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610735.1 → XP_038466663.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  2. XM_038610734.1 → XP_038466662.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  3. XM_038610737.1 → XP_038466665.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  4. XM_038610738.1 → XP_038466666.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    10965262..11086973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546743.1 → XP_038402671.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  2. XM_038546742.1 → XP_038402670.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  3. XM_038546744.1 → XP_038402672.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  4. XM_038546746.1 → XP_038402674.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    16731937..16853765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_845930.6 → XP_851023.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  2. XM_005624291.3 → XP_005624348.3  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2T9, A0A8C0SD18, A0A8I3NBF5
    Conserved Domains (1) summary
    cd06617
    Location:51 → 333
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  3. XM_022422870.2 → XP_022278578.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

  4. XM_005624292.4 → XP_005624349.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SD18
    Conserved Domains (1) summary
    cd06617
    Location:1 → 277
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
Nucleotide Protein
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