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NUMB NUMB endocytic adaptor protein [ Canis lupus familiaris (dog) ]

Gene ID: 480381, updated on 5-Mar-2024

Summary

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Official Symbol
NUMBprovided by VGNC
Official Full Name
NUMB endocytic adaptor proteinprovided by VGNC
Primary source
VGNC:VGNC:49933
See related
Ensembl:ENSCAFG00845012636
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (46848975..47010155, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (46305647..46465562, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (46923765..47086380, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (46516801..46677888, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (46532509..46695082, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene presenilin 1 Neighboring gene L-lactate dehydrogenase B chain-like Neighboring gene papilin, proteoglycan like sulfated glycoprotein Neighboring gene akirin-1-like Neighboring gene succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like Neighboring gene HEAT repeat containing 4 Neighboring gene uncharacterized LOC119872897 Neighboring gene ribosomal oxygenase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling. Wang Z, et al. EMBO J, 2009 Aug 19. PMID 19609305, Free PMC Article
  2. Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation. Lau KM, et al. Exp Cell Res, 2011 Feb 15. PMID 21147098
  3. Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif. Su JF, et al. J Cell Sci, 2016 Aug 15. PMID 27358480

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Numb is a pivotal adaptor protein that mediates the subcellular localization of EAAT3 through binding the YxNxxF (where x stands for any amino acid) motif.
    Title: Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.
  2. Numb acts to suppress Rac1-GTP accumulation, and its loss leads to increased sensitivity toward extracellular signals that disrupt cell-cell adhesion to induce epithelial-mesenchymal transition (EMT) and cell dispersal
    Title: Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation.
  3. Study identifies Numb as an important regulator of epithelial polarity and cell-cell adhesion and a sensor of HGF signalling or Src activity during Epithelial-mesenchymal transition.
    Title: Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein numb homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    46848975..47010155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674124.1 → XP_038530052.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  2. XM_038674136.1 → XP_038530064.1  protein numb homolog isoform X10

    UniProtKB/TrEMBL
    A0A8C0JW66, A0A8C0PDJ2
    Related
    ENSCAFP00845017676.1, ENSCAFT00845022512.1
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  3. XM_038674133.1 → XP_038530061.1  protein numb homolog isoform X7

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QQE4
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  4. XM_038674130.1 → XP_038530058.1  protein numb homolog isoform X4

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  5. XM_038674135.1 → XP_038530063.1  protein numb homolog isoform X9

    UniProtKB/TrEMBL
    A0A8C0JV25, A0A8C0PDJ2, A0A8C0QLA9
    Related
    ENSCAFP00845017826.1, ENSCAFT00845022732.1
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  6. XM_038674132.1 → XP_038530060.1  protein numb homolog isoform X6

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QGS8, A0A8I3NNH9
    Related
    ENSCAFP00845017786.1, ENSCAFT00845022679.1
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  7. XM_038674128.1 → XP_038530056.1  protein numb homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  8. XM_038674137.1 → XP_038530065.1  protein numb homolog isoform X11

    UniProtKB/TrEMBL
    A0A8C0QGV2
    Conserved Domains (1) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain

  9. XM_038674129.1 → XP_038530057.1  protein numb homolog isoform X3

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:258 → 336
    NumbF; NUMB domain

  10. XM_038674134.1 → XP_038530062.1  protein numb homolog isoform X8

    UniProtKB/TrEMBL
    A0A8C0PDJ2
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  11. XM_038674131.1 → XP_038530059.1  protein numb homolog isoform X5

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  12. XM_038674123.1 → XP_038530051.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  13. XM_038674125.1 → XP_038530053.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  14. XM_038674126.1 → XP_038530054.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  15. XM_038674127.1 → XP_038530055.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    46516801..46677888 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038483723.1 → XP_038339651.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  2. XM_038483735.1 → XP_038339663.1  protein numb homolog isoform X10

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  3. XM_038483732.1 → XP_038339660.1  protein numb homolog isoform X7

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  4. XM_038483729.1 → XP_038339657.1  protein numb homolog isoform X4

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  5. XM_038483734.1 → XP_038339662.1  protein numb homolog isoform X9

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  6. XM_038483731.1 → XP_038339659.1  protein numb homolog isoform X6

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  7. XM_038483727.1 → XP_038339655.1  protein numb homolog isoform X2

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  8. XM_038483736.1 → XP_038339664.1  protein numb homolog isoform X11

    Conserved Domains (1) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain

  9. XM_038483728.1 → XP_038339656.1  protein numb homolog isoform X3

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:258 → 336
    NumbF; NUMB domain

  10. XM_038483733.1 → XP_038339661.1  protein numb homolog isoform X8

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  11. XM_038483730.1 → XP_038339658.1  protein numb homolog isoform X5

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  12. XM_038483722.1 → XP_038339650.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  13. XM_038483724.1 → XP_038339652.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  14. XM_038483725.1 → XP_038339653.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  15. XM_038483726.1 → XP_038339654.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    46532509..46695082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609295.1 → XP_038465223.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  2. XM_038609307.1 → XP_038465235.1  protein numb homolog isoform X10

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  3. XM_038609304.1 → XP_038465232.1  protein numb homolog isoform X7

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  4. XM_038609301.1 → XP_038465229.1  protein numb homolog isoform X4

    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  5. XM_038609306.1 → XP_038465234.1  protein numb homolog isoform X9

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  6. XM_038609303.1 → XP_038465231.1  protein numb homolog isoform X6

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  7. XM_038609299.1 → XP_038465227.1  protein numb homolog isoform X2

    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  8. XM_038609308.1 → XP_038465236.1  protein numb homolog isoform X11

    Conserved Domains (1) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain

  9. XM_038609300.1 → XP_038465228.1  protein numb homolog isoform X3

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:258 → 336
    NumbF; NUMB domain

  10. XM_038609305.1 → XP_038465233.1  protein numb homolog isoform X8

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  11. XM_038609302.1 → XP_038465230.1  protein numb homolog isoform X5

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  12. XM_038609294.1 → XP_038465222.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  13. XM_038609296.1 → XP_038465224.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  14. XM_038609298.1 → XP_038465226.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  15. XM_038609297.1 → XP_038465225.1  protein numb homolog isoform X1

    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    46923765..47086380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545196.1 → XP_038401124.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  2. XM_038545209.1 → XP_038401137.1  protein numb homolog isoform X10

    UniProtKB/TrEMBL
    A0A8C0JW66, A0A8C0PDJ2
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  3. XM_038545205.1 → XP_038401133.1  protein numb homolog isoform X7

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QQE4
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  4. XM_038545202.1 → XP_038401130.1  protein numb homolog isoform X4

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  5. XM_038545208.1 → XP_038401136.1  protein numb homolog isoform X9

    UniProtKB/TrEMBL
    A0A8C0JV25, A0A8C0PDJ2, A0A8C0QLA9
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  6. XM_038545204.1 → XP_038401132.1  protein numb homolog isoform X6

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QGS8, A0A8I3NNH9
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  7. XM_038545200.1 → XP_038401128.1  protein numb homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  8. XM_038545210.1 → XP_038401138.1  protein numb homolog isoform X11

    UniProtKB/TrEMBL
    A0A8C0QGV2
    Conserved Domains (1) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain

  9. XM_038545201.1 → XP_038401129.1  protein numb homolog isoform X3

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:258 → 336
    NumbF; NUMB domain

  10. XM_038545207.1 → XP_038401135.1  protein numb homolog isoform X8

    UniProtKB/TrEMBL
    A0A8C0PDJ2
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  11. XM_038545203.1 → XP_038401131.1  protein numb homolog isoform X5

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  12. XM_038545194.1 → XP_038401122.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  13. XM_038545197.1 → XP_038401125.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  14. XM_038545198.1 → XP_038401126.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  15. XM_038545199.1 → XP_038401127.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    46305647..46465562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038590659.1 → XP_038446587.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  2. XM_022422199.2 → XP_022277907.1  protein numb homolog isoform X10

    UniProtKB/TrEMBL
    A0A8C0JW66, A0A8C0PDJ2
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  3. XM_014116041.3 → XP_013971516.1  protein numb homolog isoform X7

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QQE4
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  4. XM_022422196.2 → XP_022277904.1  protein numb homolog isoform X4

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 157
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:249 → 327
    NumbF; NUMB domain

  5. XM_022422198.2 → XP_022277906.1  protein numb homolog isoform X9

    UniProtKB/TrEMBL
    A0A8C0JV25, A0A8C0PDJ2, A0A8C0QLA9
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  6. XM_022422197.2 → XP_022277905.1  protein numb homolog isoform X6

    UniProtKB/TrEMBL
    A0A8C0P5H5, A0A8C0QGS8, A0A8I3NNH9
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  7. XM_022422191.2 → XP_022277899.1  protein numb homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 168
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:260 → 338
    NumbF; NUMB domain

  8. XM_038590735.1 → XP_038446663.1  protein numb homolog isoform X11

    UniProtKB/TrEMBL
    A0A8C0QGV2
    Conserved Domains (1) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain

  9. XM_038590690.1 → XP_038446618.1  protein numb homolog isoform X3

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:258 → 336
    NumbF; NUMB domain

  10. XM_038590717.1 → XP_038446645.1  protein numb homolog isoform X8

    UniProtKB/TrEMBL
    A0A8C0PDJ2
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  11. XM_038590709.1 → XP_038446637.1  protein numb homolog isoform X5

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  12. XM_038590648.1 → XP_038446576.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  13. XM_038590670.1 → XP_038446598.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  14. XM_038590677.1 → XP_038446605.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain

  15. XM_038590684.1 → XP_038446612.1  protein numb homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0P5H5
    Conserved Domains (2) summary
    cd01268
    Location:23 → 169
    PTB_Numb; Numb Phosphotyrosine-binding (PTB) domain
    pfam06311
    Location:261 → 339
    NumbF; NUMB domain
Nucleotide Protein
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