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PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Canis lupus familiaris (dog) ]

Gene ID: 480255, updated on 5-Mar-2024

Summary

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Official Symbol
PCK2provided by VGNC
Official Full Name
phosphoenolpyruvate carboxykinase 2, mitochondrialprovided by VGNC
Primary source
VGNC:VGNC:44308
See related
Ensembl:ENSCAFG00845004487
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PCK2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (4209738..4219816)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (4020846..4030924)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (4224247..4234326)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (3900384..3910462)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (3962137..3972205)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene DDB1 and CUL4 associated factor 11 Neighboring gene fat storage inducing transmembrane protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial
XP_038338758.1
XP_038400192.1
XP_038464309.1
XP_038529116.1
XP_537379.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    4209738..4219816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673188.1 → XP_038529116.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVN3, A0A8I3MN02
    Related
    ENSCAFP00845006358.1, ENSCAFT00845008092.1
    Conserved Domains (1) summary
    cd00819
    Location:44 → 633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    3900384..3910462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482830.1 → XP_038338758.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    3962137..3972205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608381.1 → XP_038464309.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    Conserved Domains (1) summary
    cd00819
    Location:44 → 633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    4224247..4234326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544264.1 → XP_038400192.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVN3, A0A8I3MN02
    Conserved Domains (1) summary
    cd00819
    Location:44 → 633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4020846..4030924
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537379.7 → XP_537379.2  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JVN3, A0A8I3MN02
    Conserved Domains (1) summary
    cd00819
    Location:44 → 633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
Nucleotide Protein
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