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PDPK1 3-phosphoinositide dependent protein kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 479875, updated on 5-Mar-2024

Summary

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Official Symbol
PDPK1provided by VGNC
Official Full Name
3-phosphoinositide dependent protein kinase 1provided by VGNC
Primary source
VGNC:VGNC:54055
See related
Ensembl:ENSCAFG00845003792
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (38736122..38815513, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (39665293..39744671, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (38869968..38949380, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (38421263..38500661, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (38393915..38473291, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene serine protease 27 Neighboring gene potassium channel tetramerization domain containing 5 Neighboring gene amidohydrolase domain containing 2 Neighboring gene ATPase H+ transporting V0 subunit c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-phosphoinositide-dependent protein kinase 1
XP_005621734.1
XP_005621737.1
XP_005621738.1
XP_013970158.1
XP_022275939.1
XP_038335355.1
XP_038335356.1
XP_038335357.1
XP_038335358.1
XP_038335359.1
XP_038335360.1
XP_038396614.1
XP_038396615.1
XP_038396616.1
XP_038396617.1
XP_038396618.1
XP_038396619.1
XP_038405427.1
XP_038460736.1
XP_038460737.1
XP_038460738.1
XP_038460739.1
XP_038460741.1
XP_038460742.1
XP_038525421.1
XP_038525422.1
XP_038525423.1
XP_038525424.1
XP_038525425.1
XP_038525426.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    38736122..38815513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669498.1 → XP_038525426.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Related
    ENSCAFP00845005443.1, ENSCAFT00845006833.1
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  2. XM_038669495.1 → XP_038525423.1  3-phosphoinositide-dependent protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:440 → 546
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:79 → 341
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  3. XM_038669493.1 → XP_038525421.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:445 → 551
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:84 → 346
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  4. XM_038669496.1 → XP_038525424.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  5. XM_038669494.1 → XP_038525422.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LQF6
    Related
    ENSCAFP00845005391.1, ENSCAFT00845006778.1
    Conserved Domains (2) summary
    cd01262
    Location:443 → 549
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:82 → 344
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  6. XM_038669497.1 → XP_038525425.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    38421263..38500661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038479432.1 → XP_038335360.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  2. XM_038479429.1 → XP_038335357.1  3-phosphoinositide-dependent protein kinase 1 isoform X3

    Conserved Domains (2) summary
    cd01262
    Location:440 → 546
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:79 → 341
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  3. XM_038479427.1 → XP_038335355.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

    Conserved Domains (2) summary
    cd01262
    Location:445 → 551
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:84 → 346
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  4. XM_038479430.1 → XP_038335358.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  5. XM_038479428.1 → XP_038335356.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

    Conserved Domains (2) summary
    cd01262
    Location:443 → 549
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:82 → 344
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  6. XM_038479431.1 → XP_038335359.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    38393915..38473291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038604814.1 → XP_038460742.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  2. XM_038604810.1 → XP_038460738.1  3-phosphoinositide-dependent protein kinase 1 isoform X3

    Conserved Domains (2) summary
    cd01262
    Location:440 → 546
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:79 → 341
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  3. XM_038604808.1 → XP_038460736.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

    Conserved Domains (2) summary
    cd01262
    Location:445 → 551
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:84 → 346
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  4. XM_038604811.1 → XP_038460739.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  5. XM_038604809.1 → XP_038460737.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

    Conserved Domains (2) summary
    cd01262
    Location:443 → 549
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:82 → 344
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  6. XM_038604813.1 → XP_038460741.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    38869968..38949380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038540691.1 → XP_038396619.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  2. XM_038540688.1 → XP_038396616.1  3-phosphoinositide-dependent protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:440 → 546
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:79 → 341
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  3. XM_038540686.1 → XP_038396614.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:445 → 551
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:84 → 346
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  4. XM_038540689.1 → XP_038396617.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  5. XM_038540687.1 → XP_038396615.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LQF6
    Conserved Domains (2) summary
    cd01262
    Location:443 → 549
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:82 → 344
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  6. XM_038540690.1 → XP_038396618.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39665293..39744671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005621681.4 → XP_005621738.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    See identical proteins and their annotated locations for XP_005621738.1

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  2. XM_005621677.4 → XP_005621734.1  3-phosphoinositide-dependent protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:440 → 546
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:79 → 341
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  3. XM_014114683.3 → XP_013970158.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:445 → 551
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:84 → 346
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  4. XM_005621680.4 → XP_005621737.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    See identical proteins and their annotated locations for XP_005621737.1

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  5. XM_038549499.1 → XP_038405427.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LQF6
    Conserved Domains (2) summary
    cd01262
    Location:443 → 549
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:82 → 344
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

  6. XM_022420231.2 → XP_022275939.1  3-phosphoinositide-dependent protein kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3RRN6, A0A8P0NK92
    Conserved Domains (2) summary
    cd01262
    Location:416 → 522
    PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
    cd05581
    Location:55 → 317
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
Nucleotide Protein
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