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LCAT lecithin-cholesterol acyltransferase [ Canis lupus familiaris (dog) ]

Gene ID: 479680, updated on 5-Mar-2024

Summary

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Official Symbol
LCATprovided by VGNC
Official Full Name
lecithin-cholesterol acyltransferaseprovided by VGNC
Primary source
VGNC:VGNC:42606
See related
Ensembl:ENSCAFG00845012245
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (81991308..81994637)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (81545969..81549297)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (82141864..82145195)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (81817519..81820847)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (81499651..81502979)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene dipeptidase 3 Neighboring gene solute carrier family 12 member 4 Neighboring gene proteasome 20S subunit beta 10 Neighboring gene chymotrypsin like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Common plasma protein marker LCAT in aggressive human breast cancer and canine mammary tumor. Park HM, et al. BMB Rep, 2020 Dec. PMID 33298249, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Common plasma protein marker LCAT in aggressive human breast cancer and canine mammary tumor.
    Title: Common plasma protein marker LCAT in aggressive human breast cancer and canine mammary tumor.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylcholine-sterol O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylcholine-sterol acyltransferase
XP_038333269.1
XP_038333270.1
XP_038385758.1
XP_038394470.1
XP_038394471.1
XP_038458587.1
XP_038458588.1
XP_038523197.1
XP_038523198.1
XP_851673.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    81991308..81994637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667269.1 → XP_038523197.1  phosphatidylcholine-sterol acyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A8I3NBK0, A0A8P0PKY5
    Related
    ENSCAFP00845017432.1, ENSCAFT00845022170.1
    Conserved Domains (1) summary
    pfam02450
    Location:84 → 409
    LCAT; Lecithin:cholesterol acyltransferase

  2. XM_038667270.1 → XP_038523198.1  phosphatidylcholine-sterol acyltransferase isoform X2

    UniProtKB/TrEMBL
    A0A8C0L222, A0A8C0NJ18
    Conserved Domains (1) summary
    pfam02450
    Location:81 → 406
    LCAT; Lecithin:cholesterol acyltransferase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    81817519..81820847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477341.1 → XP_038333269.1  phosphatidylcholine-sterol acyltransferase isoform X1

    Conserved Domains (1) summary
    pfam02450
    Location:84 → 409
    LCAT; Lecithin:cholesterol acyltransferase

  2. XM_038477342.1 → XP_038333270.1  phosphatidylcholine-sterol acyltransferase isoform X2

    Conserved Domains (1) summary
    pfam02450
    Location:81 → 406
    LCAT; Lecithin:cholesterol acyltransferase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    81499651..81502979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038602659.1 → XP_038458587.1  phosphatidylcholine-sterol acyltransferase isoform X1

  2. XM_038602660.1 → XP_038458588.1  phosphatidylcholine-sterol acyltransferase isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    82141864..82145195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038538542.1 → XP_038394470.1  phosphatidylcholine-sterol acyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A8I3NBK0, A0A8P0PKY5
    Conserved Domains (1) summary
    pfam02450
    Location:84 → 409
    LCAT; Lecithin:cholesterol acyltransferase

  2. XM_038538543.1 → XP_038394471.1  phosphatidylcholine-sterol acyltransferase isoform X2

    UniProtKB/TrEMBL
    A0A8C0L222, A0A8C0NJ18
    Conserved Domains (1) summary
    pfam02450
    Location:81 → 406
    LCAT; Lecithin:cholesterol acyltransferase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    81545969..81549297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038529830.1 → XP_038385758.1  phosphatidylcholine-sterol acyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A8I3NBK0, A0A8P0PKY5
    Conserved Domains (1) summary
    pfam02450
    Location:84 → 409
    LCAT; Lecithin:cholesterol acyltransferase

  2. XM_846580.5 → XP_851673.1  phosphatidylcholine-sterol acyltransferase isoform X2

    UniProtKB/TrEMBL
    A0A8C0L222, A0A8C0NJ18
    Conserved Domains (1) summary
    pfam02450
    Location:81 → 406
    LCAT; Lecithin:cholesterol acyltransferase
Nucleotide Protein
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