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PTTG1 PTTG1 regulator of sister chromatid separation, securin [ Canis lupus familiaris (dog) ]

Gene ID: 479307, updated on 5-Mar-2024

Summary

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Gene symbol
PTTG1
Gene description
PTTG1 regulator of sister chromatid separation, securin
See related
Ensembl:ENSCAFG00845001057
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (50737382..50745152, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (50197498..50205256, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (51189832..51197602, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (50545760..50553525, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (50669501..50677252, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119881462 Neighboring gene microRNA mir-146a Neighboring gene uncharacterized LOC111095716 Neighboring gene SLU7 homolog, splicing factor Neighboring gene family with sequence similarity 200 member C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The mRNA expression of PTTG1 is a strong prognostic indicator for recurrence after hypophysectomy in dogs with corticotroph pituitary adenomas. Vastenhout N, et al. Vet J, 2018 Oct. PMID 30268327

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The mRNA expression of PTTG1 is a strong prognostic indicator for recurrence after hypophysectomy in dogs with corticotroph pituitary adenomas.
    Title: The mRNA expression of PTTG1 is a strong prognostic indicator for recurrence after hypophysectomy in dogs with corticotroph pituitary adenomas.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in chromosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
securin
Names
pituitary tumor-transforming 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    50737382..50745152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663470.1 → XP_038519398.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  2. XM_038663467.1 → XP_038519395.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  3. XM_038663469.1 → XP_038519397.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  4. XM_038663471.1 → XP_038519399.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  5. XM_038663468.1 → XP_038519396.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Related
    ENSCAFP00845001431.1, ENSCAFT00845001817.1
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    50545760..50553525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473783.1 → XP_038329711.1  securin isoform X2

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  2. XM_038473780.1 → XP_038329708.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  3. XM_038473782.1 → XP_038329710.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  4. XM_038473785.1 → XP_038329713.1  securin isoform X2

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  5. XM_038473784.1 → XP_038329712.1  securin isoform X2

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  6. XM_038473781.1 → XP_038329709.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    50669501..50677252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599164.1 → XP_038455092.1  securin isoform X2

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  2. XM_038599161.1 → XP_038455089.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  3. XM_038599163.1 → XP_038455091.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  4. XM_038599165.1 → XP_038455093.1  securin isoform X2

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  5. XM_038599162.1 → XP_038455090.1  securin isoform X1

    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    51189832..51197602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534862.1 → XP_038390790.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  2. XM_038534859.1 → XP_038390787.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  3. XM_038534861.1 → XP_038390789.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  4. XM_038534864.1 → XP_038390792.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  5. XM_038534863.1 → XP_038390791.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  6. XM_038534860.1 → XP_038390788.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    50197498..50205256 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022417738.2 → XP_022273446.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  2. XM_536445.6 → XP_536445.2  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  3. XM_022417737.2 → XP_022273445.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor

  4. XM_038496300.1 → XP_038352228.1  securin isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBN3
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 179
    Securin; Securin sister-chromatid separation inhibitor

  5. XM_038496274.1 → XP_038352202.1  securin isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJM9, A0A8C0NBN3, A0A8C0RJL2, A0A8I3MGC4
    Conserved Domains (1) summary
    pfam04856
    Location:1 → 180
    Securin; Securin sister-chromatid separation inhibitor
Nucleotide Protein
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