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APC APC regulator of WNT signaling pathway [ Canis lupus familiaris (dog) ]

Gene ID: 479139, updated on 5-Mar-2024

Summary

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Official Symbol
APCprovided by VGNC
Official Full Name
APC regulator of WNT signaling pathwayprovided by VGNC
Primary source
VGNC:VGNC:99669
See related
Ensembl:ENSCAFG00845003519
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (93843..224101, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (1652296..1781970, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (249524..377618, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (86997..217003, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (86045..214151, complement)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558478 Neighboring gene signal recognition particle 19 Neighboring gene uncharacterized LOC111094968 Neighboring gene erythrocyte membrane protein band 4.1 like 4A Neighboring gene vegetative cell wall protein gp1-like Neighboring gene small nucleolar RNA SNORA13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. APC is a component of an organizing template for cortical microtubule networks. Reilein A, et al. Nat Cell Biol, 2005 May. PMID 15892196, Free PMC Article
  2. Colocalization of APC and DLG at the tips of cellular protrusions in cultured epithelial cells and its dependency on cytoskeletons. Iizuka-Kogo A, et al. Histochem Cell Biol, 2005 Jan. PMID 15609045
  3. Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions. Faux MC, et al. PLoS One, 2010 Nov 30. PMID 21152425, Free PMC Article
  4. Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. Sharma M, et al. J Biol Chem, 2006 Jun 23. PMID 16621792

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest that localised regulation of APC-phospho-beta-catenin complexes may contribute to the tumour suppressor activity of APC.
    Title: Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions.
  2. beta-catenin is a regulator of APC targeting to membrane clusters; both proteins have roles in cell migration
    Title: Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.
  3. APC is a component of a cortical template that guides microtubule network formation.
    Title: APC is a component of an organizing template for cortical microtubule networks.
  4. DLG functions not only at the lateral cell-cell contact sites of polarized epithelial cells but also at the protrusions of non-polarized epithelial cells through the interaction with APC protein
    Title: Colocalization of APC and DLG at the tips of cellular protrusions in cultured epithelial cells and its dependency on cytoskeletons.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables gamma-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of microtubule depolymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pattern specification process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenomatous polyposis coli protein
Names
APC, WNT signaling pathway regulator
adenomatosis polyposis coli

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    93843..224101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038660622.1 → XP_038516550.1  adenomatous polyposis coli protein isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8C0S146, A0A8I3MM67
    Related
    ENSCAFP00845005036.1, ENSCAFT00845006339.1
    Conserved Domains (17) summary
    smart00185
    Location:629 → 669
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:8 → 234
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:543 → 575
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:671 → 711
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1617 → 1640
    APC_r; APC repeat
    pfam05924
    Location:2014 → 2033
    SAMP; SAMP Motif
    pfam05937
    Location:2651 → 2824
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2204 → 2549
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 178
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:712 → 999
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1016 → 1115
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1263 → 1348
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1642 → 1695
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1726 → 1819
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1847 → 1927
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:355 → 428
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_038660626.1 → XP_038516554.1  adenomatous polyposis coli protein isoform X6

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:548 → 588
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:364 → 407
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:590 → 630
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1536 → 1559
    APC_r; APC repeat
    pfam05924
    Location:1933 → 1952
    SAMP; SAMP Motif
    pfam05937
    Location:2570 → 2743
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2123 → 2468
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:631 → 918
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:935 → 1034
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1182 → 1267
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1561 → 1614
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1645 → 1738
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1766 → 1846
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_038660625.1 → XP_038516553.1  adenomatous polyposis coli protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0NAL4, A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:566 → 606
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:480 → 512
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:608 → 648
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1554 → 1577
    APC_r; APC repeat
    pfam05924
    Location:1951 → 1970
    SAMP; SAMP Motif
    pfam05937
    Location:2588 → 2761
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2141 → 2486
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:649 → 936
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:953 → 1052
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1200 → 1285
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1579 → 1632
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1663 → 1756
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1784 → 1864
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  4. XM_038660621.1 → XP_038516549.1  adenomatous polyposis coli protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8I3MP89, A0A8P0TBE2
    Related
    ENSCAFP00845005001.1, ENSCAFT00845006298.1
    Conserved Domains (17) summary
    smart00185
    Location:649 → 689
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:465 → 508
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:691 → 731
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1637 → 1660
    APC_r; APC repeat
    pfam05924
    Location:2034 → 2053
    SAMP; SAMP Motif
    pfam05937
    Location:2671 → 2844
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2224 → 2569
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:732 → 1019
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1036 → 1135
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1283 → 1368
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1662 → 1715
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1746 → 1839
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1867 → 1947
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  5. XM_038660620.1 → XP_038516548.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Related
    ENSCAFP00845004981.1, ENSCAFT00845006274.1
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  6. XM_038660619.1 → XP_038516547.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  7. XM_038660618.1 → XP_038516546.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  8. XM_038660623.1 → XP_038516551.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

  9. XM_038660624.1 → XP_038516552.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    86997..217003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038471204.1 → XP_038327132.1  adenomatous polyposis coli protein isoform X3

    Conserved Domains (17) summary
    smart00185
    Location:629 → 669
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:8 → 234
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:543 → 575
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:671 → 711
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1617 → 1640
    APC_r; APC repeat
    pfam05924
    Location:2014 → 2033
    SAMP; SAMP Motif
    pfam05937
    Location:2651 → 2824
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2204 → 2549
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 178
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:712 → 999
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1016 → 1115
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1263 → 1348
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1642 → 1695
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1726 → 1819
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1847 → 1927
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:355 → 428
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_038471208.1 → XP_038327136.1  adenomatous polyposis coli protein isoform X6

    Conserved Domains (17) summary
    smart00185
    Location:548 → 588
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:364 → 407
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:590 → 630
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1536 → 1559
    APC_r; APC repeat
    pfam05924
    Location:1933 → 1952
    SAMP; SAMP Motif
    pfam05937
    Location:2570 → 2743
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2123 → 2468
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:631 → 918
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:935 → 1034
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1182 → 1267
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1561 → 1614
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1645 → 1738
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1766 → 1846
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_038471207.1 → XP_038327135.1  adenomatous polyposis coli protein isoform X5

    Conserved Domains (17) summary
    smart00185
    Location:566 → 606
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:480 → 512
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:608 → 648
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1554 → 1577
    APC_r; APC repeat
    pfam05924
    Location:1951 → 1970
    SAMP; SAMP Motif
    pfam05937
    Location:2588 → 2761
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2141 → 2486
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:649 → 936
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:953 → 1052
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1200 → 1285
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1579 → 1632
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1663 → 1756
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1784 → 1864
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  4. XM_038471203.1 → XP_038327131.1  adenomatous polyposis coli protein isoform X2

    Conserved Domains (17) summary
    smart00185
    Location:649 → 689
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:465 → 508
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:691 → 731
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1637 → 1660
    APC_r; APC repeat
    pfam05924
    Location:2034 → 2053
    SAMP; SAMP Motif
    pfam05937
    Location:2671 → 2844
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2224 → 2569
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:732 → 1019
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1036 → 1135
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1283 → 1368
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1662 → 1715
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1746 → 1839
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1867 → 1947
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  5. XM_038471202.1 → XP_038327130.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  6. XM_038471201.1 → XP_038327129.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  7. XM_038471200.1 → XP_038327128.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  8. XM_038471205.1 → XP_038327133.1  adenomatous polyposis coli protein isoform X4

    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

  9. XM_038471206.1 → XP_038327134.1  adenomatous polyposis coli protein isoform X4

    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    86045..214151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038596394.1 → XP_038452322.1  adenomatous polyposis coli protein isoform X3

    Conserved Domains (17) summary
    smart00185
    Location:629 → 669
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:8 → 234
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:543 → 575
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:671 → 711
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1617 → 1640
    APC_r; APC repeat
    pfam05924
    Location:2014 → 2033
    SAMP; SAMP Motif
    pfam05937
    Location:2651 → 2824
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2204 → 2549
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 178
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:712 → 999
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1016 → 1115
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1263 → 1348
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1642 → 1695
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1726 → 1819
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1847 → 1927
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:355 → 428
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_038596398.1 → XP_038452326.1  adenomatous polyposis coli protein isoform X6

    Conserved Domains (17) summary
    smart00185
    Location:548 → 588
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:364 → 407
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:590 → 630
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1536 → 1559
    APC_r; APC repeat
    pfam05924
    Location:1933 → 1952
    SAMP; SAMP Motif
    pfam05937
    Location:2570 → 2743
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2123 → 2468
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:631 → 918
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:935 → 1034
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1182 → 1267
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1561 → 1614
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1645 → 1738
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1766 → 1846
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_038596397.1 → XP_038452325.1  adenomatous polyposis coli protein isoform X5

    Conserved Domains (17) summary
    smart00185
    Location:566 → 606
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:480 → 512
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:608 → 648
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1554 → 1577
    APC_r; APC repeat
    pfam05924
    Location:1951 → 1970
    SAMP; SAMP Motif
    pfam05937
    Location:2588 → 2761
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2141 → 2486
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:649 → 936
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:953 → 1052
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1200 → 1285
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1579 → 1632
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1663 → 1756
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1784 → 1864
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  4. XM_038596393.1 → XP_038452321.1  adenomatous polyposis coli protein isoform X2

    Conserved Domains (17) summary
    smart00185
    Location:649 → 689
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:465 → 508
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:691 → 731
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1637 → 1660
    APC_r; APC repeat
    pfam05924
    Location:2034 → 2053
    SAMP; SAMP Motif
    pfam05937
    Location:2671 → 2844
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2224 → 2569
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:732 → 1019
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1036 → 1135
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1283 → 1368
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1662 → 1715
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1746 → 1839
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1867 → 1947
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  5. XM_038596392.1 → XP_038452320.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  6. XM_038596391.1 → XP_038452319.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  7. XM_038596390.1 → XP_038452318.1  adenomatous polyposis coli protein isoform X1

    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  8. XM_038596395.1 → XP_038452323.1  adenomatous polyposis coli protein isoform X4

    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

  9. XM_038596396.1 → XP_038452324.1  adenomatous polyposis coli protein isoform X4

    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    249524..377618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038532138.1 → XP_038388066.1  adenomatous polyposis coli protein isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8C0S146, A0A8I3MM67
    Conserved Domains (17) summary
    smart00185
    Location:629 → 669
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:8 → 234
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:543 → 575
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:671 → 711
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1617 → 1640
    APC_r; APC repeat
    pfam05924
    Location:2014 → 2033
    SAMP; SAMP Motif
    pfam05937
    Location:2651 → 2824
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2204 → 2549
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 178
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:712 → 999
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1016 → 1115
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1263 → 1348
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1642 → 1695
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1726 → 1819
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1847 → 1927
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:355 → 428
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_038532142.1 → XP_038388070.1  adenomatous polyposis coli protein isoform X6

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:548 → 588
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:364 → 407
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:590 → 630
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1536 → 1559
    APC_r; APC repeat
    pfam05924
    Location:1933 → 1952
    SAMP; SAMP Motif
    pfam05937
    Location:2570 → 2743
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2123 → 2468
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:631 → 918
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:935 → 1034
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1182 → 1267
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1561 → 1614
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1645 → 1738
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1766 → 1846
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_038532141.1 → XP_038388069.1  adenomatous polyposis coli protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0NAL4, A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:566 → 606
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:480 → 512
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:608 → 648
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1554 → 1577
    APC_r; APC repeat
    pfam05924
    Location:1951 → 1970
    SAMP; SAMP Motif
    pfam05937
    Location:2588 → 2761
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2141 → 2486
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:649 → 936
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:953 → 1052
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1200 → 1285
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1579 → 1632
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1663 → 1756
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1784 → 1864
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  4. XM_038532137.1 → XP_038388065.1  adenomatous polyposis coli protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8I3MP89, A0A8P0TBE2
    Conserved Domains (17) summary
    smart00185
    Location:649 → 689
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:465 → 508
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:691 → 731
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1637 → 1660
    APC_r; APC repeat
    pfam05924
    Location:2034 → 2053
    SAMP; SAMP Motif
    pfam05937
    Location:2671 → 2844
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2224 → 2569
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:732 → 1019
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1036 → 1135
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1283 → 1368
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1662 → 1715
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1746 → 1839
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1867 → 1947
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  5. XM_038532136.1 → XP_038388064.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  6. XM_038532135.1 → XP_038388063.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  7. XM_038532134.1 → XP_038388062.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  8. XM_038532139.1 → XP_038388067.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

  9. XM_038532140.1 → XP_038388068.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1652296..1781970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467879.1 → XP_038323807.1  adenomatous polyposis coli protein isoform X3

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8C0S146, A0A8I3MM67
    Conserved Domains (17) summary
    smart00185
    Location:629 → 669
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:8 → 234
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:543 → 575
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:671 → 711
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1617 → 1640
    APC_r; APC repeat
    pfam05924
    Location:2014 → 2033
    SAMP; SAMP Motif
    pfam05937
    Location:2651 → 2824
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2204 → 2549
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 178
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:712 → 999
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1016 → 1115
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1263 → 1348
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1642 → 1695
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1726 → 1819
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1847 → 1927
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:355 → 428
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_038467912.1 → XP_038323840.1  adenomatous polyposis coli protein isoform X6

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:548 → 588
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:364 → 407
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:590 → 630
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1536 → 1559
    APC_r; APC repeat
    pfam05924
    Location:1933 → 1952
    SAMP; SAMP Motif
    pfam05937
    Location:2570 → 2743
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2123 → 2468
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:631 → 918
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:935 → 1034
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1182 → 1267
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1561 → 1614
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1645 → 1738
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1766 → 1846
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_038467905.1 → XP_038323833.1  adenomatous polyposis coli protein isoform X5

    UniProtKB/TrEMBL
    A0A8C0NAL4, A0A8C0NDP1, A0A8I3RRG0
    Conserved Domains (17) summary
    smart00185
    Location:566 → 606
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:480 → 512
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:608 → 648
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1554 → 1577
    APC_r; APC repeat
    pfam05924
    Location:1951 → 1970
    SAMP; SAMP Motif
    pfam05937
    Location:2588 → 2761
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2141 → 2486
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:649 → 936
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:953 → 1052
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1200 → 1285
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1579 → 1632
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1663 → 1756
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1784 → 1864
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:307 → 365
    APC_rep; Adenomatous polyposis coli (APC) repeat

  4. XM_038467870.1 → XP_038323798.1  adenomatous polyposis coli protein isoform X2

    UniProtKB/TrEMBL
    A0A8C0N9F1, A0A8I3MP89, A0A8P0TBE2
    Conserved Domains (17) summary
    smart00185
    Location:649 → 689
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:465 → 508
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:691 → 731
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1637 → 1660
    APC_r; APC repeat
    pfam05924
    Location:2034 → 2053
    SAMP; SAMP Motif
    pfam05937
    Location:2671 → 2844
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2224 → 2569
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:732 → 1019
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1036 → 1135
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1283 → 1368
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1662 → 1715
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1746 → 1839
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1867 → 1947
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  5. XM_038467860.1 → XP_038323788.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  6. XM_038467850.1 → XP_038323778.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  7. XM_038467841.1 → XP_038323769.1  adenomatous polyposis coli protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0NDP1, A0A8C0QRU8, A0A8I3N5P5, A0A8I3RRG0
    Conserved Domains (18) summary
    PTZ00449
    Location:1356 → 1724
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00185
    Location:667 → 707
    ARM; Armadillo/beta-catenin-like repeats
    COG1196
    Location:14 → 262
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    sd00043
    Location:581 → 613
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:4 → 55
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:709 → 749
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1655 → 1678
    APC_r; APC repeat
    pfam05924
    Location:2052 → 2071
    SAMP; SAMP Motif
    pfam05937
    Location:2689 → 2862
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2242 → 2587
    APC_basic; APC basic domain
    pfam11414
    Location:127 → 207
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:750 → 1037
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:1054 → 1153
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1301 → 1386
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1680 → 1733
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1764 → 1857
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1885 → 1965
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:393 → 466
    APC_rep; Adenomatous polyposis coli (APC) repeat

  8. XM_038467888.1 → XP_038323816.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat

  9. XM_038467897.1 → XP_038323825.1  adenomatous polyposis coli protein isoform X4

    UniProtKB/TrEMBL
    A0A8C0NE00, A0A8C0QMN8, A0A8P0TGU6
    Conserved Domains (15) summary
    smart00185
    Location:608 → 648
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:522 → 554
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:650 → 690
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1596 → 1619
    APC_r; APC repeat
    pfam05924
    Location:1993 → 2012
    SAMP; SAMP Motif
    pfam05937
    Location:2630 → 2803
    EB1_binding; EB-1 Binding Domain
    pfam05956
    Location:2183 → 2528
    APC_basic; APC basic domain
    pfam11414
    Location:68 → 148
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:691 → 978
    Arm_APC_u3; Armadillo-associated region on APC
    pfam16630
    Location:995 → 1094
    APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
    pfam16633
    Location:1242 → 1327
    APC_u9; Unstructured region on APC between 1st two creatine-rich regions
    pfam16634
    Location:1621 → 1674
    APC_u13; Unstructured region on APC between APC_crr and SAMP
    pfam16635
    Location:1705 → 1798
    APC_u14; Unstructured region on APC between SAMP and APC_crr
    pfam16636
    Location:1826 → 1906
    APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
    pfam18797
    Location:334 → 407
    APC_rep; Adenomatous polyposis coli (APC) repeat
Nucleotide Protein
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