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Taf5 TBP-associated factor 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47900, updated on 4-Apr-2024

Summary

Official Symbol
Taf5provided by FlyBase
Official Full Name
TBP-associated factor 5provided by FlyBase
Primary source
FLYBASE:FBgn0010356
Locus tag
Dmel_CG7704
See related
AllianceGenome:FB:FBgn0010356
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7704; d80; Dmel\CG7704; dmTaf5; dmTAF5; dTAF5; dTAFii80; dTAFII85; dTAF[[II]]80; p85; TAF; taf5; TAF5; Taf80; TAF80; TAF80/85; Taf85; TAFII80; TAFII85; TAF[II]80; TAF[[II]]; Taf[[II]]80; TAF[[II]]80; TAF[[II]]80/85; TAF[[II]]85; TFIID; TFIID 85
Summary
Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription initiation from RNA polymerase II promoter. Located in nucleus. Part of transcription factor TFIID complex. Is expressed in male accessory gland; organism; seminal vesicle; and testis. Orthologous to human TAF5 (TATA-box binding protein associated factor 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Taf5 in Genome Data Viewer
Location:
47C5-47C5; 2-63 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10877312..10879673, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6764817..6767178, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene no child left behind Neighboring gene Peroxin 6 Neighboring gene Hydroxyacid oxidase

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
TBP-associated factor 5
Names
CG7704-PA
TBP associated factor 80
TBP-associated factor
TBP-associated factor 80
TBP-associated factor 80kD
Taf5-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10877312..10879673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057609.6NP_476957.1  TBP-associated factor 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476957.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49846, Q9V5R1
    Related
    FBpp0087335
    Conserved Domains (4) summary
    cd08044
    Location:114245
    TAF5_NTD2; TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID)
    COG2319
    Location:319674
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:373646
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:380448
    7WD40; WD40 repeat [structural motif]