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PPOX protoporphyrinogen oxidase [ Canis lupus familiaris (dog) ]

Gene ID: 478980, updated on 5-Mar-2024

Summary

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Official Symbol
PPOXprovided by VGNC
Official Full Name
protoporphyrinogen oxidaseprovided by VGNC
Primary source
VGNC:VGNC:44874
See related
Ensembl:ENSCAFG00845029591
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PPOX in Genome Data Viewer
Location:
chromosome: 38
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 38 NC_051842.1 (21424824..21428556, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 38 NC_006620.4 (21381833..21385563, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 38 NC_049259.1 (22136240..22139973, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 38 NC_049298.1 (21312659..21316388, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 38 NC_049779.1 (21727092..21730828, complement)

Chromosome 38 - NC_051842.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119868066 Neighboring gene uncharacterized LOC119868067 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 4 Neighboring gene beta-1,4-galactosyltransferase 3 Neighboring gene ubiquitin specific peptidase 21 Neighboring gene uncharacterized LOC119868068 Neighboring gene ubiquitin-fold modifier conjugating enzyme 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxygen-dependent protoporphyrinogen oxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protoporphyrinogen oxidase
XP_005640930.1
XP_022271126.1
XP_022271127.1
XP_038304550.1
XP_038304551.1
XP_038304552.1
XP_038378435.1
XP_038378436.1
XP_038378437.1
XP_038442216.1
XP_038442217.1
XP_038442218.1
XP_038506636.1
XP_038506637.1
XP_038506638.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051842.1 Reference ROS_Cfam_1.0

    Range
    21424824..21428556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448623.1 → XP_038304551.1  protoporphyrinogen oxidase isoform X2

    Conserved Domains (1) summary
    COG1232
    Location:5 → 437
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]

  2. XM_038448622.1 → XP_038304550.1  protoporphyrinogen oxidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NVR8, A0A8I3Q7Z3
    Related
    ENSCAFP00845041163.1, ENSCAFT00845052462.1
    Conserved Domains (1) summary
    TIGR00562
    Location:3 → 474
    proto_IX_ox; protoporphyrinogen oxidase

  3. XM_038448624.1 → XP_038304552.1  protoporphyrinogen oxidase isoform X3

    Conserved Domains (1) summary
    TIGR00562
    Location:4 → 312
    proto_IX_ox; protoporphyrinogen oxidase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049298.1 Alternate UMICH_Zoey_3.1

    Range
    21312659..21316388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038522508.1 → XP_038378436.1  protoporphyrinogen oxidase isoform X2

  2. XM_038522507.1 → XP_038378435.1  protoporphyrinogen oxidase isoform X1

  3. XM_038522509.1 → XP_038378437.1  protoporphyrinogen oxidase isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049779.1 Alternate UNSW_CanFamBas_1.0

    Range
    21727092..21730828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038650709.1 → XP_038506637.1  protoporphyrinogen oxidase isoform X2

    Conserved Domains (1) summary
    COG1232
    Location:5 → 437
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]

  2. XM_038650708.1 → XP_038506636.1  protoporphyrinogen oxidase isoform X1

    Conserved Domains (1) summary
    TIGR00562
    Location:3 → 474
    proto_IX_ox; protoporphyrinogen oxidase

  3. XM_038650710.1 → XP_038506638.1  protoporphyrinogen oxidase isoform X3

    Conserved Domains (1) summary
    TIGR00562
    Location:4 → 312
    proto_IX_ox; protoporphyrinogen oxidase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049259.1 Alternate UU_Cfam_GSD_1.0

    Range
    22136240..22139973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038586289.1 → XP_038442217.1  protoporphyrinogen oxidase isoform X2

    Conserved Domains (1) summary
    COG1232
    Location:5 → 437
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]

  2. XM_038586288.1 → XP_038442216.1  protoporphyrinogen oxidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NVR8, A0A8I3Q7Z3
    Conserved Domains (1) summary
    TIGR00562
    Location:3 → 474
    proto_IX_ox; protoporphyrinogen oxidase

  3. XM_038586290.1 → XP_038442218.1  protoporphyrinogen oxidase isoform X3

    Conserved Domains (1) summary
    TIGR00562
    Location:4 → 312
    proto_IX_ox; protoporphyrinogen oxidase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006620.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21381833..21385563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022415418.2 → XP_022271126.1  protoporphyrinogen oxidase isoform X2

    Conserved Domains (1) summary
    cl27533
    Location:5 → 437
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]

  2. XM_005640873.3 → XP_005640930.1  protoporphyrinogen oxidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0SK32, A0A8P0NEL6
    Conserved Domains (3) summary
    COG1232
    Location:5 → 474
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]
    pfam13450
    Location:7 → 65
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
    cl21454
    Location:230 → 364
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_022415419.2 → XP_022271127.1  protoporphyrinogen oxidase isoform X3

    Conserved Domains (1) summary
    cl27533
    Location:4 → 312
    HemY; Protoporphyrinogen oxidase [Coenzyme transport and metabolism]
Nucleotide Protein
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