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PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [ Canis lupus familiaris (dog) ]

Gene ID: 478938, updated on 5-Mar-2024

Summary

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Official Symbol
PIK3C2Bprovided by VGNC
Official Full Name
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 betaprovided by VGNC
Primary source
VGNC:VGNC:44552
See related
Ensembl:ENSCAFG00845023047
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 38
Exon count:
37
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 38 NC_051842.1 (969737..1035426, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 38 NC_006620.4 (1069379..1134940, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 38 NC_049259.1 (1557935..1623716, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 38 NC_049298.1 (966025..1031937, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 38 NC_049779.1 (1357807..1423477, complement)

Chromosome 38 - NC_051842.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111094567 Neighboring gene protein phosphatase 1 regulatory subunit 15B Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Names
phosphoinositide-3-kinase, class 2, beta polypeptide
XP_013966701.2
XP_038304169.1
XP_038304170.1
XP_038304171.1
XP_038304172.1
XP_038304173.1
XP_038304174.1
XP_038319925.1
XP_038319926.1
XP_038319927.1
XP_038319928.1
XP_038319929.1
XP_038378104.1
XP_038378105.1
XP_038378106.1
XP_038378107.1
XP_038378108.1
XP_038378109.1
XP_038441911.1
XP_038441912.1
XP_038441913.1
XP_038441914.1
XP_038441915.1
XP_038441916.1
XP_038506306.1
XP_038506307.1
XP_038506308.1
XP_038506309.1
XP_038506310.1
XP_038506311.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051842.1 Reference ROS_Cfam_1.0

    Range
    969737..1035426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448244.1 → XP_038304172.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Related
    ENSCAFP00845032089.1, ENSCAFT00845040964.1
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_038448241.1 → XP_038304169.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Related
    ENSCAFP00845031882.1, ENSCAFT00845040727.1
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_038448242.1 → XP_038304170.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  4. XM_038448243.1 → XP_038304171.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  5. XM_038448246.1 → XP_038304174.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  6. XM_038448245.1 → XP_038304173.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:765 → 1118
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1147 → 1255
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:400 → 572
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1283 → 1405
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:591 → 759
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:142 → 244
    PI3K_rbd; PI3-kinase family, ras-binding domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049298.1 Alternate UMICH_Zoey_3.1

    Range
    966025..1031937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038522179.1 → XP_038378107.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_038522176.1 → XP_038378104.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_038522177.1 → XP_038378105.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  4. XM_038522178.1 → XP_038378106.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  5. XM_038522181.1 → XP_038378109.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  6. XM_038522180.1 → XP_038378108.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049779.1 Alternate UNSW_CanFamBas_1.0

    Range
    1357807..1423477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038650381.1 → XP_038506309.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_038650378.1 → XP_038506306.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_038650379.1 → XP_038506307.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  4. XM_038650380.1 → XP_038506308.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  5. XM_038650383.1 → XP_038506311.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  6. XM_038650382.1 → XP_038506310.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

    Conserved Domains (6) summary
    cd00895
    Location:765 → 1118
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1147 → 1255
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:400 → 572
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1283 → 1405
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:591 → 759
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:142 → 244
    PI3K_rbd; PI3-kinase family, ras-binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049259.1 Alternate UU_Cfam_GSD_1.0

    Range
    1557935..1623716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585986.1 → XP_038441914.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  2. XM_038585983.1 → XP_038441911.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  3. XM_038585984.1 → XP_038441912.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  4. XM_038585985.1 → XP_038441913.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  5. XM_038585988.1 → XP_038441916.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  6. XM_038585987.1 → XP_038441915.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (7) summary
    cd00895
    Location:765 → 1118
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1147 → 1255
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:400 → 572
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1283 → 1405
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    PRK14086
    Location:3 → 89
    dnaA; chromosomal replication initiator protein DnaA
    cd00869
    Location:591 → 759
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:142 → 244
    PI3K_rbd; PI3-kinase family, ras-binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006620.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1069379..1134940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014111226.3 → XP_013966701.2  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_038463997.1 → XP_038319925.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_038463998.1 → XP_038319926.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  4. XM_038463999.1 → XP_038319927.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0SQ87, A0A8I3PM55
    Conserved Domains (6) summary
    cd00895
    Location:988 → 1341
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1370 → 1478
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:623 → 795
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1506 → 1628
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:814 → 982
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:365 → 467
    PI3K_rbd; PI3-kinase family, ras-binding domain

  5. XM_038464001.1 → XP_038319929.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  6. XM_038464000.1 → XP_038319928.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:765 → 1118
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1147 → 1255
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:400 → 572
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1283 → 1405
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:591 → 759
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:142 → 244
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

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