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KNG1 kininogen 1 [ Canis lupus familiaris (dog) ]

Gene ID: 478666, updated on 5-Mar-2024

Summary

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Official Symbol
KNG1provided by VGNC
Official Full Name
kininogen 1provided by VGNC
Primary source
VGNC:VGNC:53466
See related
Ensembl:ENSCAFG00845021120
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human all
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Genomic context

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Location:
chromosome: 34
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (19199856..19229431)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (23373992..23403581)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (19460203..19488753)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (19231763..19260578)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (19231843..19260884)

Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene fetuin B Neighboring gene histidine rich glycoprotein Neighboring gene small nucleolar RNA SNORD2 Neighboring gene small nucleolar RNA SNORA81 Neighboring gene eukaryotic translation initiation factor 4A2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation. Dick GM, et al. Am J Physiol Heart Circ Physiol, 2006 Dec. PMID 16905596

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kininogen-1
Names
bradykinin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051838.1 Reference ROS_Cfam_1.0

    Range
    19199856..19229431
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445822.1 → XP_038301750.1  kininogen-1

    UniProtKB/TrEMBL
    A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
    Related
    ENSCAFP00845029426.1, ENSCAFT00845037560.1
    Conserved Domains (2) summary
    smart00043
    Location:264 → 371
    CY; Cystatin-like domain
    pfam00031
    Location:144 → 236
    Cystatin; Cystatin domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049294.1 Alternate UMICH_Zoey_3.1

    Range
    19231763..19260578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038520019.1 → XP_038375947.1  kininogen-1

    Conserved Domains (2) summary
    smart00043
    Location:264 → 371
    CY; Cystatin-like domain
    pfam00031
    Location:144 → 236
    Cystatin; Cystatin domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

    Range
    19231843..19260884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038648061.1 → XP_038503989.1  kininogen-1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

    Range
    19460203..19488753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583644.1 → XP_038439572.1  kininogen-1

    UniProtKB/TrEMBL
    A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
    Conserved Domains (2) summary
    smart00043
    Location:264 → 371
    CY; Cystatin-like domain
    pfam00031
    Location:144 → 236
    Cystatin; Cystatin domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23373992..23403581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535836.7 → XP_535836.1  kininogen-1

    UniProtKB/TrEMBL
    A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
    Conserved Domains (2) summary
    smart00043
    Location:264 → 371
    CY; Cystatin-like domain
    pfam00031
    Location:144 → 236
    Cystatin; Cystatin domain
Nucleotide Protein
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