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HADH hydroxyacyl-CoA dehydrogenase [ Canis lupus familiaris (dog) ]

Gene ID: 478506, updated on 5-Mar-2024

Summary

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Official Symbol
HADHprovided by VGNC
Official Full Name
hydroxyacyl-CoA dehydrogenaseprovided by VGNC
Primary source
VGNC:VGNC:41584
See related
Ensembl:ENSCAFG00845029127
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 32
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (28689480..28735351)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (13516288..13562132, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (11383587..11429427, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (28682743..28728360)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (28427283..28473178)

Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene sphingomyelin synthase 2 Neighboring gene uncharacterized LOC102151722 Neighboring gene cytochrome P450 family 2 subfamily U member 1 Neighboring gene uncharacterized LOC111093692 Neighboring gene lymphoid enhancer binding factor 1 Neighboring gene eukaryotic translation initiation factor 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-hydroxyacyl-CoA dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Names
hydroxyacyl-Coenzyme A dehydrogenase
XP_038300260.1
XP_038374648.1
XP_038437874.1
XP_038502597.1
XP_535685.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051836.1 Reference ROS_Cfam_1.0

    Range
    28689480..28735351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038444332.1 → XP_038300260.1  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0KAK2, A0A8C0PEV9, A0A8C0TB33
    Related
    ENSCAFP00845040527.1, ENSCAFT00845051653.1
    Conserved Domains (1) summary
    COG1250
    Location:27 → 313
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049292.1 Alternate UMICH_Zoey_3.1

    Range
    28682743..28728360
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038518720.1 → XP_038374648.1  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    Conserved Domains (1) summary
    COG1250
    Location:27 → 313
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

    Range
    28427283..28473178
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038646669.1 → XP_038502597.1  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    Conserved Domains (1) summary
    COG1250
    Location:27 → 313
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

    Range
    11383587..11429427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038581946.1 → XP_038437874.1  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0KAK2, A0A8C0PEV9, A0A8C0TB33
    Conserved Domains (1) summary
    COG1250
    Location:27 → 313
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13516288..13562132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535685.7 → XP_535685.2  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

    See identical proteins and their annotated locations for XP_535685.2

    UniProtKB/TrEMBL
    A0A8C0PEV9, A0A8P0TBX0
    Conserved Domains (3) summary
    COG1250
    Location:25 → 311
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]
    pfam00725
    Location:214 → 311
    3HCDH; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
    pfam02737
    Location:27 → 212
    3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Nucleotide Protein
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